Khalid N M Abdelazeem
Overview
Explore the profile of Khalid N M Abdelazeem including associated specialties, affiliations and a list of published articles.
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13
Citations
97
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Recent Articles
1.
Abdelazeem K, Nguyen D, Corbo S, Darragh L, Matsumoto M, Van Court B, et al.
Oncogene
. 2024 Nov;
44(3):130-146.
PMID: 39489818
The EphB4-ephrinB2 signaling axis has been heavily implicated in metastasis across numerous cancer types. Our emerging understanding of the dichotomous roles that EphB4 and ephrinB2 play in head and neck...
2.
Van Court B, Ciccaglione M, Neupert B, Knitz M, Maroney S, Nguyen D, et al.
bioRxiv
. 2024 Oct;
PMID: 39386624
Recently developed ultrasound contrast agents are a promising tool for imaging and drug delivery in tumors. To better understand their unusual kinetics, we implemented a novel pixel clustering analysis, which...
3.
Corbo S, Nguyen D, Bhatia S, Darragh L, Abdelazeem K, Van Court B, et al.
bioRxiv
. 2024 Aug;
PMID: 39211197
Significance: EphA4 in regulatory T cells has a pro-tumoral effect while EphA4 in macrophages plays an anti-tumoral role underscoring the necessity of developing biologically rational therapeutics.
4.
Abdelazeem K, Nguyen D, Corbo S, Darragh L, Matsumoto M, Van Court B, et al.
bioRxiv
. 2024 Aug;
PMID: 39091728
The EphB4-ephrinB2 signaling axis has been heavily implicated in metastasis across numerous cancer types. Our emerging understanding of the dichotomous roles that EphB4 and ephrinB2 play in head and neck...
5.
Yu J, Gadwa J, Ross R, Knitz M, Darragh L, Abdelazeem K, et al.
Cancer Immunol Immunother
. 2024 Mar;
73(5):90.
PMID: 38554147
Clinically approved head and neck squamous cell carcinoma (HNSCC) immunotherapies manipulate the immune checkpoint blockade (ICB) axis but have had limited success outside of recurrent/metastatic disease. Interleukin-7 (IL7) has been...
6.
Darragh L, Nguyen A, Pham T, Idlett-Ali S, Knitz M, Gadwa J, et al.
Med
. 2024 Feb;
5(3):254-270.e8.
PMID: 38423011
Background: Perineural invasion (PNI) and nerve density within the tumor microenvironment (TME) have long been associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). This prompted an...
7.
Ross R, Gadwa J, Yu J, Darragh L, Knitz M, Nguyen D, et al.
Clin Cancer Res
. 2024 Feb;
30(9):1916-1933.
PMID: 38363297
Purpose: Head and neck cancer (HNC) improvements are stagnant, even with advances in immunotherapy. Our previous clinical trial data show that altered fatty acid (FA) metabolism correlates with outcome. We...
8.
Piper M, Hoen M, Darragh L, Knitz M, Nguyen D, Gadwa J, et al.
Cancer Cell
. 2023 Apr;
41(5):950-969.e6.
PMID: 37116489
In pancreatic ductal adenocarcinoma (PDAC) patients, we show that response to radiation therapy (RT) is characterized by increased IL-2Rβ and IL-2Rγ along with decreased IL-2Rα expression. The bispecific PD1-IL2v is...
9.
Wang Y, Tan L, Jiao K, Xue C, Tang Q, Jiang S, et al.
Br J Pharmacol
. 2022 Jun;
179(20):4792-4808.
PMID: 35771623
Background And Purpose: Atopic dermatitis (AD) is one of the most common chronic inflammatory cutaneous diseases with unmet clinical needs. As a common ingredient found in several medicinal herbs with...
10.
Abdelazeem K, Kalo M, Beer-Hammer S, Lang F
Sci Rep
. 2021 Mar;
11(1):7117.
PMID: 33782464
Inflammation is a natural defense process of the innate immune system, associated with the release of proinflammatory cytokines such as interleukin-1β, interleukin-6, interleukin-12 and TNFα; and enzymes including iNOS through...