Keyan Zarei
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Explore the profile of Keyan Zarei including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
124
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Recent Articles
1.
OMalley Y, Zarei K, Vanegas O, Singh P, Apak T, Coleman M, et al.
J Cyst Fibros
. 2023 Aug;
23(1):169-171.
PMID: 37633792
Pancreatic secretions become viscous and acidic in Cystic fibrosis (CF), highlighting the role of CFTR in pancreatic fluid and bicarbonate secretion. Forskolin-induced swelling (FIS) assay developed in intestinal organoids measures...
2.
Zarei K, Thornell I, Stoltz D
Front Physiol
. 2022 Jun;
13:882525.
PMID: 35685290
Fluid and anion secretion are important functions of the biliary tract. It has been established that cAMP regulates Na absorption through NHE3. However, mechanisms of gallbladder anion transport are less...
3.
Yu W, Moninger T, Thurman A, Xie Y, Jain A, Zarei K, et al.
Proc Natl Acad Sci U S A
. 2022 Jan;
119(4).
PMID: 35046051
Submucosal glands (SMGs) protect lungs but can also contribute to disease. For example, in cystic fibrosis (CF), SMGs produce abnormal mucus that disrupts mucociliary transport. CF is an ion transport...
4.
Farzam K, Zarei K
Cureus
. 2021 Dec;
13(12):r38.
PMID: 34926100
[This retracts the article DOI: 10.7759/cureus.17850.].
5.
Farzam K, Zarei K
Cureus
. 2021 Sep;
13(9):e17850.
PMID: 34522562
Light chain deposition disease (LCDD) is a rare cause of kidney failure. It is associated with multiple myeloma and is diagnosed by the evaluation of serum and urine free light...
6.
Zarei K, Meyerholz D, Stoltz D
Physiol Rep
. 2021 Jul;
9(14):e14978.
PMID: 34288572
Hepatobiliary disease causes significant morbidity and mortality in people with cystic fibrosis (CF), yet this problem remains understudied. Previous studies in the newborn CF pig demonstrated decreased bile flow into...
7.
Ostedgaard L, Price M, Whitworth K, Abou Alaiwa M, Fischer A, Warrier A, et al.
Elife
. 2020 Oct;
9.
PMID: 33026343
Submucosal glands (SMGs) are a prominent structure that lines human cartilaginous airways. Although it has been assumed that SMGs contribute to respiratory defense, that hypothesis has gone without a direct...
8.
Zarei K, Stroik M, Gansemer N, Thurman A, Ostedgaard L, Ernst S, et al.
Lab Invest
. 2020 Jul;
100(11):1388-1399.
PMID: 32719544
Hepatobiliary disease causes significant morbidity in people with cystic fibrosis (CF), yet this problem remains understudied. We previously found that newborn CF pigs have microgallbladders with significant luminal obstruction in...
9.
Fischer A, Pino-Argumedo M, Hilkin B, Shanrock C, Gansemer N, Chaly A, et al.
JCI Insight
. 2019 Jan;
4(1).
PMID: 30626743
Mucus produced by submucosal glands is a key component of respiratory mucociliary transport (MCT). When it emerges from submucosal gland ducts, mucus forms long strands on the airway surface. However,...
10.
Cook D, Adam R, Zarei K, Deonovic B, Stroik M, Gansemer N, et al.
JCI Insight
. 2017 Sep;
2(17).
PMID: 28878137
Abnormal airway smooth muscle function can contribute to cystic fibrosis (CF) airway disease. We previously found that airway smooth muscle from newborn CF pigs had increased basal tone, an increased...