Kevin Woollard
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Explore the profile of Kevin Woollard including associated specialties, affiliations and a list of published articles.
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12
Citations
841
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Recent Articles
1.
Tumlin J, Rovin B, Anders H, Mysler E, Jayne D, Takeuchi T, et al.
Kidney Int Rep
. 2025 Jan;
10(1):29-39.
PMID: 39810777
Type I interferons (IFNs) are immunostimulatory molecules that can activate the innate and adaptive immune systems. In cases of immune dysfunction, prolonged activation of the type I IFN pathway has...
2.
Chihomvu P, Ganesan A, Gibbons S, Woollard K, Hayes M
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201478
Phytochemicals have a long and successful history in drug discovery. With recent advancements in analytical techniques and methodologies, discovering bioactive leads from natural compounds has become easier. Computational techniques like...
3.
Hofherr A, Liarte Marin E, Musial B, Seth A, Slidel T, Conway J, et al.
Kidney Int Rep
. 2024 Jun;
9(6):1876-1891.
PMID: 38899206
Introduction: Inflammation is a significant contributor to cardiorenal morbidity and mortality in diabetic kidney disease (DKD). The pathophysiological mechanisms linking systemic, subacute inflammation and local, kidney injury-initiated immune maladaptation is...
4.
Prendecki M, Gulati K, Turner-Stokes T, Bhangal G, Chiappo D, Woollard K, et al.
J Pathol
. 2021 Jun;
255(2):107-119.
PMID: 34124781
Experimental autoimmune vasculitis (EAV) is a model of antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) induced by immunisation of susceptible rat strains with myeloperoxidase (MPO). Animals develop circulating MPO-ANCA, pulmonary haemorrhage,...
5.
George M, Jasmin N, Cummings V, Richard-Loendt A, Launchbury F, Woollard K, et al.
JACC Basic Transl Sci
. 2021 Jun;
6(5):431-443.
PMID: 34095633
Interleukin (IL)-6 is an emerging therapeutic target in myocardial infarction (MI). IL-6 has 2 distinct signaling pathways: trans-signaling, which mediates inflammation, and classic signaling, which also has anti-inflammatory effects. The...
6.
Siggins M, Lynskey N, Lamb L, Johnson L, Huse K, Pearson M, et al.
Nat Commun
. 2020 Sep;
11(1):4697.
PMID: 32943639
Unassisted metastasis through the lymphatic system is a mechanism of dissemination thus far ascribed only to cancer cells. Here, we report that Streptococcus pyogenes also hijack lymphatic vessels to escape...
7.
8.
Constantinescu-Bercu A, Grassi L, Frontini M, Salles-Crawley I, Woollard K, Crawley J
Elife
. 2020 Apr;
9.
PMID: 32314961
Platelet-neutrophil interactions are important for innate immunity, but also contribute to the pathogenesis of deep vein thrombosis, myocardial infarction and stroke. Here we report that, under flow, von Willebrand factor/glycoprotein...
9.
Rahman M, Woollard K
Adv Exp Med Biol
. 2017 Jul;
1003:121-144.
PMID: 28667557
In this chapter, we discuss the manner through which the immune system regulates the cardiovascular system in health and disease. We define the cardiovascular system and elements of atherosclerotic disease,...
10.
Garcia Diaz A, Moyon B, Coan P, Alfazema N, Venda L, Woollard K, et al.
Dis Model Mech
. 2016 Jan;
9(4):463-71.
PMID: 26769799
The Wistar Kyoto (WKY) rat and the spontaneously hypertensive (SHR) rat inbred strains are well-established models for human crescentic glomerulonephritis (CRGN) and metabolic syndrome, respectively. Novel transgenic (Tg) strains add...