Kevin V Lemley
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Explore the profile of Kevin V Lemley including associated specialties, affiliations and a list of published articles.
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86
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2393
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Recent Articles
1.
Villani V, Frank C, Cravedi P, Hou X, Bin S, Kamitakahara A, et al.
Sci Transl Med
. 2024 Oct;
16(771):eadl5514.
PMID: 39475573
Cycles of a fasting-mimicking diet (FMD) promote regeneration and reduce damage in the pancreases, blood, guts, and nervous systems of mice, but their effect on kidney disease is unknown. In...
2.
Clair G, Soloyan H, Cravedi P, Angeletti A, Salem F, Al-Rabadi L, et al.
JCI Insight
. 2024 Mar;
9(6).
PMID: 38516889
Here, we used digital spatial profiling (DSP) to describe the glomerular transcriptomic signatures that may characterize the complex molecular mechanisms underlying progressive kidney disease in Alport syndrome, focal segmental glomerulosclerosis,...
3.
Zhang Q, Bin S, Budge K, Petrosyan A, Villani V, Aguiari P, et al.
JCI Insight
. 2024 Jan;
9(4).
PMID: 38227377
The deposition of antipodocyte autoantibodies in the glomerular subepithelial space induces primary membranous nephropathy (MN), the leading cause of nephrotic syndrome worldwide. Taking advantage of the glomerulus-on-a-chip system, we modeled...
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Saulnier P, Looker H, Layton A, Lemley K, Nelson R, Bjornstad P
Diabetes
. 2023 Aug;
72(11):1682-1691.
PMID: 37586079
Article Highlights:
7.
Petrosyan A, Villani V, Aguiari P, Thornton M, Wang Y, Rajewski A, et al.
Adv Sci (Weinh)
. 2023 Apr;
10(20):e2206787.
PMID: 37114795
A nephrogenic progenitor cell (NP) with cancer stem cell characteristics driving Wilms tumor (WT) using spatial transcriptomics, bulk and single cell RNA sequencing, and complementary in vitro and transplantation experiments...
8.
Srivastava T, Dell K, Lemley K, Gipson D, Kaskel F, Meyers K, et al.
Glomerular Dis
. 2023 Feb;
2(4):176-183.
PMID: 36817288
Introduction: Minimal change disease in childhood can follow a frequently relapsing or steroid-dependent course in up to 40% of cases. Second-line immunosuppressive medications that are used to manage these patients...
9.
Lemley K
Glomerular Dis
. 2023 Feb;
1(4):294-301.
PMID: 36751381
Background: Stereology is the science of inferring quantitative features of 3-dimensional structures from lower dimensional samples of those structures (probes). It is a statistical discipline and therefore may seem intimidating...
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Primack W, Chevalier R, Friedman A, Lemley K, Norwood V, Schwartz G, et al.
Pediatr Nephrol
. 2023 Jan;
38(12):3947-3954.
PMID: 36625931
The International Study of Kidney Disease in Children (ISKDC), begun in 1966, conducted the first international collaborative randomized blinded controlled trial in pediatric nephrology and one of the first in...