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Kevin Sheehan

Explore the profile of Kevin Sheehan including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 245
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Recent Articles
1.
Berton M, Sheehan K, Adamo A, McQuade D
Beilstein J Org Chem . 2020 Jun; 16:1343-1356. PMID: 32595782
Magnesium organometallic reagents occupy a central position in organic synthesis. The freshness of these compounds is the key for achieving a high conversion and reproducible results. Common methods for the...
2.
Frank M, Khodadoust M, Czerwinski D, Haabeth O, Chu M, Miklos D, et al.
J Exp Med . 2020 Jun; 217(9). PMID: 32558897
Here, we report on the results of a phase I/II trial (NCT00490529) for patients with mantle cell lymphoma who, having achieved remission after immunochemotherapy, were vaccinated with irradiated, CpG-activated tumor...
3.
Busque S, Scandling J, Lowsky R, Shizuru J, Jensen K, Waters J, et al.
Sci Transl Med . 2020 Jan; 12(528). PMID: 31996467
Preclinical studies have shown that persistent mixed chimerism is linked to acceptance of organ allografts without immunosuppressive (IS) drugs. Mixed chimerism refers to continued mixing of donor and recipient hematopoietic...
4.
Meyer E, Laport G, Xie B, MacDonald K, Heydari K, Sahaf B, et al.
JCI Insight . 2019 May; 4(10). PMID: 31092732
BACKGROUNDIn preclinical murine and early clinical studies of hematopoietic cell transplantation, engineering of donor grafts with defined ratios of CD4+CD25+FoxP3+ Tregs to conventional T cells (Tcons) results in the prevention...
5.
Muffly L, Sheehan K, Armstrong R, Jensen K, Tate K, Rezvani A, et al.
Blood Adv . 2018 Mar; 2(6):681-690. PMID: 29572391
Murine models showed that CD8CD44 memory T (T) cells could eradicate malignant cells without inducing graft-versus-host disease (GVHD). We evaluated the feasibility and safety of infusing freshly isolated and purified...
6.
Coleman C, Adams S, Adrianopoli C, Ansari A, Bader J, Buddemeier B, et al.
Biosecur Bioterror . 2012 Dec; 10(4):346-71. PMID: 23244500
This article summarizes major points from a newly released guide published online by the Office of the Assistant Secretary for Preparedness and Response (ASPR). The article reviews basic principles about...
7.
Laport G, Sheehan K, Baker J, Armstrong R, Wong R, Lowsky R, et al.
Biol Blood Marrow Transplant . 2011 Jun; 17(11):1679-87. PMID: 21664472
Donor leukocyte infusions induce remissions in some patients with hematologic malignancies who relapse after allogeneic hematopoietic cell transplantation (HCT); however, graft-versus-host disease (GVHD) remains the major complication of this strategy....
8.
Pyne D, Saunders P, Montgomery P, Hewitt A, Sheehan K
J Strength Cond Res . 2008 Aug; 22(5):1633-7. PMID: 18714221
Repeated sprint testing is gaining popularity in team sports, but the methods of data analysis and relationships to speed and endurance qualities are not well described. We compared three different...
9.
Cao T, Wong R, Sheehan K, Laport G, Stockerl-Goldstein K, Johnston L, et al.
Exp Hematol . 2005 Feb; 33(3):279-85. PMID: 15730851
Objectives: Optimal granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cell (G-PBMC) graft compositions for myeloablative allogeneic hematopoietic cell transplantation (AHCT) have not been identified. G-PBMC cell contents were analyzed for influence...
10.
Cao T, Shizuru J, Wong R, Sheehan K, Laport G, Stockerl-Goldstein K, et al.
Blood . 2004 Dec; 105(6):2300-6. PMID: 15572597
The influence of graft composition on clinical outcomes after reduced-intensity conditioning is not well-characterized. In this report we prospectively enumerated CD34+, CD3+, CD4+, and CD8+ cell doses in granulocyte colony-stimulating...