Kevin P Francis
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Explore the profile of Kevin P Francis including associated specialties, affiliations and a list of published articles.
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Articles
86
Citations
2547
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Recent Articles
1.
Wiener J, Sanghvi P, Vlastaris K, Mroz T, Belding J, Kaelber D, et al.
Spine (Phila Pa 1976)
. 2025 Feb;
PMID: 39895110
Study Design: retrospective cohort study. Objective: To investigate the relationship between perioperative Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) and postoperative outcomes after spinal fusion in obese and diabetic patient populations....
2.
Graham J, Castro J, Werba L, Fardone L, Francis K, Ramamurthi A, et al.
bioRxiv
. 2024 Oct;
PMID: 39386541
CRISPR gene editing offers unprecedented genomic and transcriptomic control for precise regulation of cell function and phenotype. However, delivering the necessary CRISPR components to therapeutically relevant cell types without cytotoxicity...
3.
Blaskovich M, Hansford K, Butler M, Ramu S, Kavanagh A, Jarrad A, et al.
Sci Transl Med
. 2022 Sep;
14(662):eabj2381.
PMID: 36103517
Drug-resistant Gram-positive bacterial infections are still a substantial burden on the public health system, with two bacteria ( and ) accounting for over 1.5 million drug-resistant infections in the United...
4.
Kenney D, OConnell A, Turcinovic J, Montanaro P, Hekman R, Tamura T, et al.
Cell Rep
. 2022 Apr;
39(3):110714.
PMID: 35421379
The human immunological mechanisms defining the clinical outcome of SARS-CoV-2 infection remain elusive. This knowledge gap is mostly driven by the lack of appropriate experimental platforms recapitulating human immune responses...
5.
Wang Y, Borthwell R, Hori K, Clarkson S, Blumstein G, Park H, et al.
J Biomed Mater Res B Appl Biomater
. 2022 Mar;
110(8):1932-1941.
PMID: 35352867
Preclinical in vitro and in vivo methods to study bacterial interactions with dermal fillers and infection pathogenesis are lacking. In this work, first in vitro methods to assess protein biofouling...
6.
Carossino M, Kenney D, OConnell A, Montanaro P, Tseng A, Gertje H, et al.
Viruses
. 2022 Mar;
14(3).
PMID: 35336942
Animal models recapitulating COVID-19 are critical to enhance our understanding of SARS-CoV-2 pathogenesis. Intranasally inoculated transgenic mice expressing human angiotensin-converting enzyme 2 under the cytokeratin 18 promoter (K18-hACE2) represent a...
7.
Carpia F, Slate A, Bandyopadhyay S, Wojczyk B, Godbey E, Francis K, et al.
Br J Haematol
. 2021 Nov;
196(4):1105-1110.
PMID: 34726258
Transfusion of storage-damaged red blood cells (RBCs) increases non-transferrin-bound iron (NTBI) levels in humans. This can potentially enhance virulence of microorganisms. In this study, Pseudomonas aeruginosa replication and biofilm production...
8.
Yevtodiyenko A, Bazhin A, Khodakivskyi P, Godinat A, Budin G, Maric T, et al.
Nat Commun
. 2021 May;
12(1):2680.
PMID: 33976191
Bioluminescent imaging (BLI) is one of the most powerful and widely used preclinical imaging modalities. However, the current technology relies on the use of transgenic luciferase-expressing cells and animals and...
9.
Carossino M, Montanaro P, OConnell A, Kenney D, Gertje H, Grosz K, et al.
bioRxiv
. 2021 Jan;
PMID: 33469581
Animal models recapitulating distinctive features of severe COVID-19 are critical to enhance our understanding of SARS-CoV-2 pathogenesis. Transgenic mice expressing human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter...
10.
Park H, Zoller S, Hegde V, Sheppard W, Burke Z, Blumstein G, et al.
Sci Rep
. 2021 Jan;
11(1):1622.
PMID: 33452271
Implant-associated infections are challenging to diagnose and treat. Fluorescent probes have been heralded as a technologic advancement that can improve our ability to non-invasively identify infecting organisms, as well as...