Kevin Lebrigand
Overview
Explore the profile of Kevin Lebrigand including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
2704
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Recent Articles
1.
Vasquez-Pacheco E, Marega M, Lingampally A, Fassy J, Truchi M, Goth K, et al.
Theranostics
. 2024 Jul;
14(9):3603-3622.
PMID: 38948058
Myofibroblasts (MYFs) are generally considered the principal culprits in excessive extracellular matrix deposition and scar formation in the pathogenesis of lung fibrosis. Lipofibroblasts (LIFs), on the other hand, are defined...
2.
Copley R, Buttin J, Arguel M, Williaume G, Lebrigand K, Barbry P, et al.
Dev Biol
. 2024 Jun;
514:1-11.
PMID: 38878991
In chordates, the central nervous system arises from precursors that have distinct developmental and transcriptional trajectories. Anterior nervous systems are ontogenically associated with ectodermal lineages while posterior nervous systems are...
3.
Redman E, Fierville M, Cavard A, Plaisant M, Arguel M, Ruiz Garcia S, et al.
Am J Respir Cell Mol Biol
. 2024 Jun;
71(3):267-281.
PMID: 38843491
The human airway mucociliary epithelium can be recapitulated using primary cells cultured in an air-liquid interface (ALI), a reliable surrogate to perform pathophysiological studies. As tremendous variations exist among media...
4.
Kypraios A, Bennour J, Imbert V, David L, Calvo J, Pflumio F, et al.
Cancers (Basel)
. 2024 May;
16(9).
PMID: 38730619
Pediatric T-cell Acute Lymphoblastic Leukemia (T-ALL) relapses are still associated with a dismal outcome, justifying the search for new therapeutic targets and relapse biomarkers. Using single-cell RNA sequencing (scRNAseq) data...
5.
Truchi M, Lacoux C, Gille C, Fassy J, Magnone V, Lopes Goncalves R, et al.
Front Bioinform
. 2024 Mar;
4:1340339.
PMID: 38501112
Single-cell CRISPR-based transcriptome screens are potent genetic tools for concomitantly assessing the expression profiles of cells targeted by a set of guides RNA (gRNA), and inferring target gene functions from...
6.
Zaragosi L, Gouleau A, Delin M, Lebrigand K, Arguel M, Girard-Riboulleau C, et al.
Methods Mol Biol
. 2023 Oct;
2725:1-25.
PMID: 37856015
The study of the airway epithelium in vitro is routinely performed using air-liquid culture (ALI) models from nasal or bronchial basal cells. These 3D experimental models allow to follow the...
7.
Guilbaud E, Barouillet T, Ilie M, Borowczyk C, Ivanov S, Sarrazy V, et al.
Cell Stem Cell
. 2023 Jun;
30(6):800-817.e9.
PMID: 37267915
Cholesterol efflux pathways could be exploited in tumor biology to unravel cancer vulnerabilities. A mouse model of lung-tumor-bearing KRAS mutation with specific disruption of cholesterol efflux pathways in epithelial progenitor...
8.
Cavard A, Redman E, Mercey O, Abelanet S, Plaisant M, Arguel M, et al.
FEBS Lett
. 2023 Apr;
597(12):1623-1637.
PMID: 37102425
The MIR449 genomic locus encompasses several regulators of multiciliated cell (MCC) formation (multiciliogenesis). The miR-449 homologs miR-34b/c represent additional regulators of multiciliogenesis that are transcribed from another locus. Here, we...
9.
Lebrigand K, Bergenstrahle J, Thrane K, Mollbrink A, Meletis K, Barbry P, et al.
Nucleic Acids Res
. 2023 Mar;
51(8):e47.
PMID: 36928528
In situ capturing technologies add tissue context to gene expression data, with the potential of providing a greater understanding of complex biological systems. However, splicing variants and full-length sequence heterogeneity...
10.
Chu X, Lingampally A, Moiseenko A, Kheirollahi V, Vazquez-Armendariz A, Koepke J, et al.
Cell Mol Life Sci
. 2022 Nov;
79(11):581.
PMID: 36333491
Repair-supportive mesenchymal cells (RSMCs) have been recently reported in the context of naphthalene (NA)-induced airway injury and regeneration. These cells transiently express smooth muscle actin (Acta2) and are enriched with...