Kevin K K Leung
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Explore the profile of Kevin K K Leung including associated specialties, affiliations and a list of published articles.
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3
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32
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Recent Articles
1.
Leung K, Shilton B
Biochemistry
. 2015 Dec;
54(51):7438-48.
PMID: 26636353
Quinone reductase 2 (NQO2) is an enzyme that might have intracellular signaling functions. NQO2 can exist in either an oxidized state or a reduced state, and binding of compounds to...
2.
Leung K, Shilton B
Biochemistry
. 2014 Nov;
54(1):47-59.
PMID: 25379648
Quinone reductase 2 (NQO2) exhibits off-target interactions with two protein kinase CK2 inhibitors, 4,5,6,7-1H-tetrabromobenzimidazole (TBBz) and 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole (DMAT). TBBz and DMAT induce apoptosis in cells expressing an inhibitor-resistant CK2, suggesting...
3.
Leung K, Shilton B
J Biol Chem
. 2013 Mar;
288(16):11242-51.
PMID: 23471972
Quinone reductase 2 (NQO2) is an FAD-linked enzyme and the only known human target of two antimalarial drugs, primaquine (PQ) and chloroquine (CQ). The structural differences between oxidized and reduced...