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Kevin Jude

Explore the profile of Kevin Jude including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 450
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Recent Articles
1.
Sockolosky J, Trotta E, Parisi G, Picton L, Su L, Le A, et al.
Science . 2018 Mar; 359(6379):1037-1042. PMID: 29496879
Interleukin-2 (IL-2) is a cytokine required for effector T cell expansion, survival, and function, especially for engineered T cells in adoptive cell immunotherapy, but its pleiotropy leads to simultaneous stimulation...
2.
Weiskopf K, Jahchan N, Schnorr P, Cristea S, Ring A, Maute R, et al.
J Clin Invest . 2016 Jun; 126(7):2610-20. PMID: 27294525
Small-cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer with limited treatment options. CD47 is a cell-surface molecule that promotes immune evasion by engaging signal-regulatory protein alpha...
3.
Moraga I, Richter D, Wilmes S, Winkelmann H, Jude K, Thomas C, et al.
Sci Signal . 2015 Nov; 8(402):ra114. PMID: 26554818
Cytokines dimerize cell surface receptors to activate signaling and regulate many facets of the immune response. Many cytokines have pleiotropic effects, inducing a spectrum of redundant and distinct effects on...
4.
Colleluori D, Reczkowski R, Emig F, Cama E, Cox J, Scolnick L, et al.
Arch Biochem Biophys . 2005 Nov; 444(1):15-26. PMID: 16266687
Rat liver arginase (arginase I) is potently inactivated by diethyl pyrocarbonate, with a second-order rate constant of 113M(-1)s(-1) for the inactivation process at pH 7.0, 25 degrees C. Partial protection...