Kevin J Schwartz
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Explore the profile of Kevin J Schwartz including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
568
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Recent Articles
11.
Peck R, Shiflett A, Schwartz K, McCann A, Hajduk S, Bangs J
Mol Microbiol
. 2008 Apr;
68(4):933-46.
PMID: 18430083
RNAi knockdown was employed to study the function of p67, a lysosome-associated membrane protein (LAMP)-like type I transmembrane lysosomal glycoprotein in African trypanosomes. Conditional induction of p67 dsRNA resulted in...
12.
McCann A, Schwartz K, Bangs J
Mol Biochem Parasitol
. 2008 Mar;
159(2):146-9.
PMID: 18359105
The lysosomal/endosomal system of African trypanosomes is developmentally regulated and is important in the pathogenesis associated with infection of the mammalian bloodstream. Long considered to be a target for drug...
13.
Moraes M, Jesus T, Hashimoto N, Dey M, Schwartz K, Alves V, et al.
Eukaryot Cell
. 2007 Sep;
6(11):1979-91.
PMID: 17873083
Translational control mediated by phosphorylation of the alpha subunit of the eukaryotic initiation factor 2 (eIF2alpha) is central to stress-induced programs of gene expression. Trypanosomatids, important human pathogens, display differentiation...
14.
Schwartz K, Bangs J
J Eukaryot Microbiol
. 2007 Feb;
54(1):22-4.
PMID: 17300513
The structure, biosynthesis, and attachment of glycosylphosphatidylinositol (GPI) anchors were all first determined for the variant surface glycoprotein (VSG) of African trypanosomes, and all of the basic aspects of this...
15.
Schwartz K, Peck R, Tazeh N, Bangs J
J Cell Sci
. 2005 Nov;
118(Pt 23):5499-511.
PMID: 16291721
Progression of GPI-anchored proteins in bloodstream African trypanosomes correlates with GPI-valence: homodimeric VSG (2 GPI) is a surface protein; heterodimeric transferrin receptor (1 GPI) localizes in the flagellar pocket; homodimeric...
16.
Hamilton H, Dominguez N, Schwartz K, Hackett K, Dillard J
Mol Microbiol
. 2005 Mar;
55(6):1704-21.
PMID: 15752195
The process of DNA donation for natural transformation of bacteria is poorly understood and has been assumed to involve bacterial cell death. Recently in Neisseria gonorrhoeae we found that mutations...
17.
Alexander D, Schwartz K, Balber A, Bangs J
J Cell Sci
. 2002 Jul;
115(Pt 16):3253-63.
PMID: 12140257
p67 is a lysosomal type I membrane glycoprotein of Trypanosoma brucei. In procyclic stage cells p67 trafficks to the lysosome without modification, but in the bloodstream stage Golgi processing adds...