Kevin J Cheung
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Explore the profile of Kevin J Cheung including associated specialties, affiliations and a list of published articles.
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24
Citations
2154
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Recent Articles
1.
Yamamoto A, Huang Y, Krajina B, McBirney M, Doak A, Qu S, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(10):e2214888120.
PMID: 36853945
Necrosis in the tumor interior is a common feature of aggressive cancers that is associated with poor clinical prognosis and the development of metastasis. How the necrotic core promotes metastasis...
2.
Yamamoto A, Doak A, Cheung K
Annu Rev Pathol
. 2022 Oct;
18:231-256.
PMID: 36207009
Metastatic dissemination has lethal consequences for cancer patients. Accruing evidence supports the hypothesis that tumor cells can migrate and metastasize as clusters of cells while maintaining contacts with one another....
3.
Xiao J, Rahbar H, Hippe D, Rendi M, Parker E, Shekar N, et al.
NPJ Breast Cancer
. 2021 Apr;
7(1):42.
PMID: 33863924
Angiogenesis is a critical component of breast cancer development, and identification of imaging-based angiogenesis assays has prognostic and treatment implications. We evaluated the association of semi-quantitative kinetic and radiomic breast...
4.
Wrenn E, Moore B, Greenwood E, McBirney M, Cheung K
J Mammary Gland Biol Neoplasia
. 2020 Oct;
25(4):337-350.
PMID: 33106923
Tumor organoids mimic the architecture and heterogeneity of in vivo tumors and enable studies of collective interactions between tumor cells as well as with their surrounding microenvironment. Although tumor organoids...
5.
Wrenn E, Yamamoto A, Moore B, Huang Y, McBirney M, Thomas A, et al.
Cell
. 2020 Oct;
183(2):395-410.e19.
PMID: 33007268
Collective metastasis is defined as the cohesive migration and metastasis of multicellular tumor cell clusters. Disrupting various cell adhesion genes markedly reduces cluster formation and colonization efficiency, yet the downstream...
6.
Padmanaban V, Grasset E, Neumann N, Fraser A, Henriet E, Matsui W, et al.
Nat Protoc
. 2020 Jul;
15(8):2413-2442.
PMID: 32690957
Cancer invasion and metastasis are challenging to study in vivo since they occur deep inside the body over extended time periods. Organotypic 3D culture of fresh tumor tissue enables convenient...
7.
Padmanaban V, Tsehay Y, Cheung K, Ewald A, Bader J
PLoS Comput Biol
. 2020 Jan;
16(1):e1007464.
PMID: 31961880
For women with access to healthcare and early detection, breast cancer deaths are caused primarily by metastasis rather than growth of the primary tumor. Metastasis has been difficult to study...
8.
Cheung K, Davidson N
J Natl Cancer Inst
. 2019 Jan;
111(7):641-643.
PMID: 30698728
No abstract available.
9.
Wrenn E, Cheung K
Dev Cell
. 2018 Dec;
47(5):539-540.
PMID: 30513297
Stem cells can enter a reversible cell-cycle arrest state termed quiescence. In this issue of Developmental Cell, Fu et al. report that the transcription factor FoxP1 is necessary for postnatal...
10.
Greenwood E, Wrenn E, Cheung K
Dev Cell
. 2017 Mar;
40(4):328-330.
PMID: 28245919
The properties of stem cells that participate in mammary gland branching morphogenesis remain contested. Reporting in Nature, Scheele et al. (2017) establish a model for post-pubertal mammary branching morphogenesis in...