Kevin J Chalut
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Explore the profile of Kevin J Chalut including associated specialties, affiliations and a list of published articles.
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1160
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Recent Articles
1.
Mulas C, Stammers M, Salomaa S, Heinzen C, Suter D, Smith A, et al.
Development
. 2024 Jul;
151(14).
PMID: 39069943
Naïve epiblast cells in the embryo and pluripotent stem cells in vitro undergo developmental progression to a formative state competent for lineage specification. During this transition, transcription factors and chromatin...
2.
Ebisuya M, Rayon T, Diaz-Cuadros M, Chalut K, Wu G, Dodd A, et al.
Dev Cell
. 2024 Jun;
59(13):1623-1627.
PMID: 38906139
A classical question in biology is how different processes are controlled in space and time, with research pointing to different mechanisms as timers. In this collection of Voices, we asked...
3.
Neumann B, Segel M, Ghosh T, Zhao C, Tourlomousis P, Young A, et al.
Nat Aging
. 2023 Apr;
1(9):826-837.
PMID: 37117631
Like many adult stem cell populations, the capacity of oligodendrocyte progenitor cells (OPCs) to proliferate and differentiate is substantially impaired with aging. Previous work has shown that tissue-wide transient expression...
4.
Miroshnikova Y, Shahbazi M, Negrete J, Chalut K, Smith A
Development
. 2023 Mar;
150(6).
PMID: 36930528
The Company of Biologists' 2022 workshop on 'Cell State Transitions: Approaches, Experimental Systems and Models' brought together an international and interdisciplinary team of investigators spanning the fields of cell and...
5.
De Belly H, Paluch E, Chalut K
Nat Rev Mol Cell Biol
. 2022 Apr;
23(7):465-480.
PMID: 35365816
Mechanical signalling affects multiple biological processes during development and in adult organisms, including cell fate transitions, cell migration, morphogenesis and immune responses. Here, we review recent insights into the mechanisms...
6.
Yanagida A, Corujo-Simon E, Revell C, Sahu P, Stirparo G, Aspalter I, et al.
Cell
. 2022 Apr;
185(7):1258.
PMID: 35364033
No abstract available.
7.
Yanagida A, Corujo-Simon E, Revell C, Sahu P, Stirparo G, Aspalter I, et al.
Cell
. 2022 Feb;
185(5):777-793.e20.
PMID: 35196500
In development, lineage segregation is coordinated in time and space. An important example is the mammalian inner cell mass, in which the primitive endoderm (PrE, founder of the yolk sac)...
8.
Mulas C, Chaigne A, Smith A, Chalut K
Development
. 2021 Dec;
148(20).
PMID: 34932803
A fundamental challenge when studying biological systems is the description of cell state dynamics. During transitions between cell states, a multitude of parameters may change - from the promoters that...
9.
Labouesse C, Tan B, Agley C, Hofer M, Winkel A, Stirparo G, et al.
Nat Commun
. 2021 Oct;
12(1):6132.
PMID: 34675200
Studies of mechanical signalling are typically performed by comparing cells cultured on soft and stiff hydrogel-based substrates. However, it is challenging to independently and robustly control both substrate stiffness and...
10.
Chaigne A, Smith M, Lopez Cavestany R, Hannezo E, Chalut K, Paluch E
J Cell Sci
. 2021 Jul;
134(14).
PMID: 34323278
Proper control of division orientation and symmetry, largely determined by spindle positioning, is essential to development and homeostasis. Spindle positioning has been extensively studied in cells dividing in two-dimensional (2D)...