Robin J M Franklin
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Explore the profile of Robin J M Franklin including associated specialties, affiliations and a list of published articles.
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213
Citations
14082
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Recent Articles
1.
Gaitsch H, Assinck P, Dimas P, Zhao C, Morcom L, Rowitch D, et al.
Brain Commun
. 2025 Jan;
7(1):fcae386.
PMID: 39830424
The extent to which glial cell turnover features in successful remyelination is unclear. In this study, the rat caudal cerebellar peduncle-ethidium bromide lesion model was used to profile oligodendroglial and...
2.
Marsh S, Walker A, Kamath T, Dissing-Olesen L, Hammond T, de Soysa T, et al.
Nat Neurosci
. 2024 Dec;
28(1):215.
PMID: 39672966
No abstract available.
3.
Heo D, Kim A, Neumann B, Doze V, Xu Y, Mironova Y, et al.
bioRxiv
. 2024 Nov;
PMID: 39554158
Oligodendrocyte progenitor cells (OPCs) are highly dynamic, widely distributed glial cells of the central nervous system (CNS) that are responsible for generating myelinating oligodendrocytes during development. By also generating new...
4.
Stockley J, Vaquie A, Xu Z, Bartels T, Jordan G, Holmqvist S, et al.
Glia
. 2024 Nov;
73(2):399-421.
PMID: 39501820
Oligodendrocytes (OLs) of the central nervous system require iron for proteolipid biosynthesis during the myelination process. Although most heme is found complexed to hemoglobin in red blood cells, surprisingly, we...
5.
Vale-Silva R, de Paes de Faria J, Seixas A, Brakebusch C, Franklin R, Relvas J
Glia
. 2024 Nov;
73(2):381-398.
PMID: 39495111
Timely differentiation and myelin formation by oligodendrocytes are essential for the physiological functioning of the central nervous system (CNS). While the Rho GTPase RhoA has been hinted as a negative...
6.
Wagstaff L, Bestard-Cuche N, Kaczmarek M, Fidanza A, McNeil L, Franklin R, et al.
Nat Commun
. 2024 Oct;
15(1):8570.
PMID: 39384784
In Multiple Sclerosis (MS), inflammatory demyelinated lesions in the brain and spinal cord lead to neurodegeneration and progressive disability. Remyelination can restore fast saltatory conduction and neuroprotection but is inefficient...
7.
Goldman S, Franklin R, Osorio J
Handb Clin Neurol
. 2024 Sep;
205:283-295.
PMID: 39341659
Much of clinical neurology is concerned with diseases of-or involving-the brain's subcortical white matter. Common to these disorders is the loss of myelin, reflecting the elimination or dysfunction of oligodendrocytes...
8.
Philp A, Reyes C, Mansilla J, Sharma A, Zhao C, Valenzuela-Krugmann C, et al.
Elife
. 2024 Aug;
12.
PMID: 39163103
Revealing unknown cues that regulate oligodendrocyte progenitor cell (OPC) function in remyelination is important to optimise the development of regenerative therapies for multiple sclerosis (MS). Platelets are present in chronic...
9.
Mei F, Fancy S, Shen Y, Niu J, Zhao C, Presley B, et al.
Nat Med
. 2024 Jul;
30(9):2692.
PMID: 38997609
No abstract available.
10.
Foerster S, Floriddia E, van Bruggen D, Kukanja P, Herve B, Cheng S, et al.
Nat Neurosci
. 2024 Jun;
27(8):1545-1554.
PMID: 38849524
In the mouse embryonic forebrain, developmentally distinct oligodendrocyte progenitor cell populations and their progeny, oligodendrocytes, emerge from three distinct regions in a spatiotemporal gradient from ventral to dorsal. However, the...