Michael G Giacomelli
Overview
Explore the profile of Michael G Giacomelli including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
566
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0
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Recent Articles
1.
Huang C, Ching-Roa V, Heckman C, Sipprell W, Ibrahim S, Smoller B, et al.
Biomed Opt Express
. 2024 Jun;
15(5):2898-2909.
PMID: 38855659
Advanced fluorescence imaging modalities such as confocal microscopy and two photon fluorescence microscopy can provide rapid, real-time histology images, but the mounting of fresh tissue specimens in standard orientations required...
2.
Huang C, Montague J, Ching-Roa V, Drage M, Ibrahim S, Giacomelli M
Biomed Opt Express
. 2024 Feb;
15(2):700-714.
PMID: 38404330
Tissue clearing methods render biological tissues transparent while maintaining tissue structure, enabling visualization of entire tissues. Recent developments in tissue clearing have predominantly emphasized preserving intrinsic fluorescent proteins or aqueous-based...
3.
Ching-Roa V, Huang C, Giacomelli M
IEEE Trans Med Imaging
. 2024 Jan;
43(6):2159-2168.
PMID: 38265914
Resonant scanning is critical to high speed and in vivo imaging in many applications of laser scanning microscopy. However, resonant scanning suffers from well-known image artifacts due to scanner jitter,...
4.
Giacomelli M
Biomed Opt Express
. 2023 Nov;
14(11):5861-5869.
PMID: 38021131
High-speed laser scanning microscopy frequently relies on resonant scanners due to their order of magnitude increase in imaging rate compared to conventional galvanometer scanners. However, the use of a nonlinear...
5.
Majeski J, Ching-Roa V, Giacomelli M, Choe R
Biomed Opt Express
. 2023 Jun;
14(6):2873-2888.
PMID: 37342692
A design for a low-cost, heterodyne, frequency domain-diffuse optical spectroscopy system is presented and validated. The system uses a single wavelength of 785 nm and a single detector to illustrate...
6.
Ching-Roa V, Huang C, Ibrahim S, Smoller B, Giacomelli M
JAMA Dermatol
. 2022 Sep;
158(10):1175-1182.
PMID: 36069886
Importance: Nonmelanoma skin cancers (NMSCs) are primarily diagnosed through paraffin section histologic analysis of skin biopsy specimens that requires days to weeks before a formal diagnosis is reported. Two-photon fluorescence...
7.
Huang C, Ching-Roa V, Liu Y, Giacomelli M
J Biomed Opt
. 2022 Jan;
27(1).
PMID: 35075830
Significance: Two-photon and confocal microscopy can obtain high frame rates; however, mosaic imaging of large tissue specimens remains time-consuming and inefficient, with higher imaging rates leading to a larger fraction...
8.
Ching-Roa V, Huang C, Giacomelli M
Biomed Opt Express
. 2021 Nov;
12(10):6461-6473.
PMID: 34745749
Microscopy with ultraviolet surface excitation (MUSE) typically has an optical sectioning thickness significantly larger than standard physical sectioning thickness, resulting in increased background fluorescence and higher feature density compared to...
9.
Ching-Roa V, Olson E, Ibrahim S, Torres R, Giacomelli M
Sci Rep
. 2021 Apr;
11(1):8476.
PMID: 33850262
No abstract available.
10.
Ching-Roa V, Olson E, Ibrahim S, Torres R, Giacomelli M
Sci Rep
. 2021 Mar;
11(1):5248.
PMID: 33664354
Conventional two-photon microscopes use photomultiplier tubes, which enable high sensitivity but can detect relatively few photons per second, forcing longer pixel integration times and limiting maximum imaging rates. We introduce...