Kevin J Barnham
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Explore the profile of Kevin J Barnham including associated specialties, affiliations and a list of published articles.
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169
Citations
6503
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Recent Articles
1.
Beauchamp L, Ellett L, Juan S, Liu X, Hunt C, Parish C, et al.
Acta Neuropathol
. 2025 Mar;
149(1):21.
PMID: 40024917
Hyposmia is one of the most prevalent non-motor symptoms of Parkinson's disease and antecedes motor dysfunction by up to a decade. However, the underlying pathophysiology remains poorly understood. In this...
2.
Purnianto A, Mawal C, Kulkarni M, Su H, Koukoulis T, Wongsodirdjo P, et al.
J Extracell Biol
. 2024 Oct;
3(10):e70012.
PMID: 39403171
Cells have developed a highly regulated system for the uptake, transport, utilization, storage, and export of metals, ensuring the maintenance of cellular homeostasis. Small extracellular vesicles (sEVs) function as a...
3.
Huang X, Fowler C, Li Y, Li Q, Sun J, Pan Y, et al.
Nat Commun
. 2024 Sep;
15(1):7998.
PMID: 39266542
Impaired clearance of amyloid β (Aβ) in late-onset Alzheimer's disease (AD) affects disease progression. The role of peripheral monocytes in Aβ clearance from the central nervous system (CNS) is unclear....
4.
Trlin P, Gong J, Tran K, Wong V, Lee P, Hoang A, et al.
Sci Rep
. 2024 Jul;
14(1):16089.
PMID: 38997314
Retinal hyperspectral imaging (HSI) is a non-invasive in vivo approach that has shown promise in Alzheimer's disease. Parkinson's disease is another neurodegenerative disease where brain pathobiology such as alpha-synuclein and...
5.
Koukoulis T, Beauchamp L, Kaparakis-Liaskos M, McQuade R, Purnianto A, Finkelstein D, et al.
J Parkinsons Dis
. 2024 Mar;
14(2):227-244.
PMID: 38427502
Parkinson's disease (PD) is an increasingly common neurodegenerative disease. It has been suggested that the etiology of idiopathic PD is complex and multifactorial involving environmental contributions, such as viral or...
6.
Bramich S, Noyce A, King A, Naismith S, Kuruvilla M, Lewis S, et al.
J Sleep Res
. 2023 Nov;
33(3):e14109.
PMID: 38014898
Isolated rapid eye movement (REM) sleep behaviour disorder (iRBD) is a sleep disorder that is characterised by dream enactment episodes during REM sleep. It is the strongest known predictor of...
7.
Beauchamp L, Dore V, Villemagne V, Xu S, Finkelstein D, Barnham K, et al.
Neurology
. 2023 Oct;
101(22):e2314-e2324.
PMID: 37816639
Background And Objectives: There are limited validated biomarkers in Parkinson disease (PD) which substantially hinders the ability to monitor disease progression and consequently measure the efficacy of disease-modifying treatments. Imaging...
8.
Su H, Masters C, Bush A, Barnham K, Reid G, Vella L
Proteomics
. 2023 Sep;
24(11):e2300063.
PMID: 37654087
Lipids play a significant role in maintaining central nervous system (CNS) structure and function, and the dysregulation of lipid metabolism is known to occur in many neurological disorders, including Alzheimer's...
9.
Keenan R, Daykin H, Metha J, Cornthwaite-Duncan L, Wright D, Clarke K, et al.
Br J Pharmacol
. 2023 Aug;
181(1):87-106.
PMID: 37553894
Background And Purpose: Tau pathology contributes to a bidirectional relationship between sleep disruption and neurodegenerative disease. Tau transgenic rTg4510 mice model tauopathy symptoms, including sleep/wake disturbances, which manifest as marked...
10.
Morgan K, de Veer M, Miles L, Kelderman C, McLean C, Masters C, et al.
Chem Commun (Camb)
. 2023 Feb;
59(16):2243-2246.
PMID: 36723107
With the aim of developing the concept of pretargeted click chemistry for the diagnosis of Alzheimer's disease two antibodies specific for amyloid-β were modified to incorporate -cyclooctene functional groups. Two...