Kevin Guertin
Overview
Explore the profile of Kevin Guertin including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
36
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0
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Recent Articles
1.
Banerjee D, Zhao L, Wu L, Palanichamy A, Ergun A, Peng L, et al.
Immunology
. 2015 Dec;
147(4):399-413.
PMID: 26694902
Retinoic acid receptor-related orphan nuclear receptor γ (RORγ) orchestrates a pro-inflammatory gene expression programme in multiple lymphocyte lineages including T helper type 17 (Th17) cells, γδ T cells, innate lymphoid...
2.
Chao J, Enyedy I, van Vloten K, Marcotte D, Guertin K, Hutchings R, et al.
Bioorg Med Chem Lett
. 2015 Jun;
25(15):2991-7.
PMID: 26048806
RORγt is a pivotal regulator of a pro-inflammatory gene expression program implicated in the pathology of several major human immune-mediated diseases. Evidence from mouse models demonstrates that genetic or pharmacological...
3.
Wang T, Banerjee D, Bohnert T, Chao J, Enyedy I, Fontenot J, et al.
Bioorg Med Chem Lett
. 2015 Jun;
25(15):2985-90.
PMID: 26048789
The nuclear receptor RORγ plays a central role in controlling a pro-inflammatory gene expression program in several lymphocyte lineages including TH17 cells. RORγ-dependent inflammation has been implicated in the pathogenesis...
4.
Cheung A, Brinkman J, Firooznia F, Flohr A, Grimsby J, Gubler M, et al.
Bioorg Med Chem Lett
. 2010 Jun;
20(14):4140-6.
PMID: 20541935
7-N-Acetamide-4-methoxy-2-aminobenzothiazole 4-fluorobenzamide (compound 1) was chosen as a drug-like and non-xanthine based starting point for the discovery of A(2B) receptor antagonists because of its slight selectivity against A(1) and A(2A)...