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Jason Fontenot

Explore the profile of Jason Fontenot including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 976
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Recent Articles
1.
Chao J, Enyedy I, van Vloten K, Marcotte D, Guertin K, Hutchings R, et al.
Bioorg Med Chem Lett . 2015 Jun; 25(15):2991-7. PMID: 26048806
RORγt is a pivotal regulator of a pro-inflammatory gene expression program implicated in the pathology of several major human immune-mediated diseases. Evidence from mouse models demonstrates that genetic or pharmacological...
2.
Wang T, Banerjee D, Bohnert T, Chao J, Enyedy I, Fontenot J, et al.
Bioorg Med Chem Lett . 2015 Jun; 25(15):2985-90. PMID: 26048789
The nuclear receptor RORγ plays a central role in controlling a pro-inflammatory gene expression program in several lymphocyte lineages including TH17 cells. RORγ-dependent inflammation has been implicated in the pathogenesis...
3.
DAlise A, Auyeung V, Feuerer M, Nishio J, Fontenot J, Benoist C, et al.
Proc Natl Acad Sci U S A . 2008 Dec; 105(50):19857-62. PMID: 19073938
FoxP3(+) regulatory T cells (Tregs) protect against autoimmunity, type 1 diabetes (T1D) in particular, prompting the hypothesis that a deficiency in Tregs is a critical determinant of diabetes susceptibility in...
4.
Rubtsov Y, Rasmussen J, Chi E, Fontenot J, Castelli L, Ye X, et al.
Immunity . 2008 Apr; 28(4):546-58. PMID: 18387831
The regulatory T (Treg) cells restrain immune responses through suppressor-function elaboration that is dependent upon expression of the transcription factor Foxp3. Despite a critical role for Treg cells in maintaining...