Kevin Dooley
Overview
Explore the profile of Kevin Dooley including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
517
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0
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Recent Articles
1.
Patel S, Schmidt K, Farhoud M, Zi T, Jang S, Dooley K, et al.
Nucl Med Biol
. 2022 Jun;
112-113:20-30.
PMID: 35763877
Methods: EVs were surface-labeled to high radiochemical purity and specific activity with Zirconium deferoxamine ([Zr]Zr-DFO) and/or cy7-scrambled antisense oligonucleotide (Cy7-ExoASO), or luminally loaded with GFP for in vivo tracking in...
2.
Kamerkar S, Leng C, Burenkova O, Jang S, McCoy C, Zhang K, et al.
Sci Adv
. 2022 Feb;
8(7):eabj7002.
PMID: 35179953
Effectiveness of checkpoint immunotherapy in cancer can be undermined by immunosuppressive tumor-associated macrophages (TAMs) with an M2 phenotype. Reprogramming TAMs toward a proinflammatory M1 phenotype is a novel approach to...
3.
Deutsch D, Edelstein M, Dooley K, Henthorn T
J Acoust Soc Am
. 2021 May;
149(4):2829.
PMID: 33940899
An experiment is reported, showing that short-term memory for pitch in absolute pitch (AP) possessors, while substantially more accurate than in AP nonpossessors, is also subject to illusory conjunctions of...
4.
Jang S, Economides K, Moniz R, Sia C, Lewis N, McCoy C, et al.
Commun Biol
. 2021 Apr;
4(1):497.
PMID: 33888863
Cyclic dinucleotide (CDN) agonists of the STimulator of InterferoN Genes (STING) pathway have shown immune activation and tumor clearance in pre-clinical models. However, CDNs administered intratumorally also promote STING activation...
5.
Dooley K, McConnell R, Xu K, Lewis N, Haupt S, Youniss M, et al.
Mol Ther
. 2021 Jan;
29(5):1729-1743.
PMID: 33484965
Extracellular vesicles (EVs) are an important intercellular communication system facilitating the transfer of macromolecules between cells. Delivery of exogenous cargo tethered to the EV surface or packaged inside the lumen...
6.
Lewis N, Sia C, Kirwin K, Haupt S, Mahimkar G, Zi T, et al.
Mol Cancer Ther
. 2021 Jan;
20(3):523-534.
PMID: 33443094
The promise of IL12 as a cancer treatment has yet to be fulfilled with multiple tested approaches being limited by unwanted systemic exposure and unpredictable pharmacology. To address these limitations,...
7.
Lin A, Clapp M, Karanja E, Dooley K, Weihl C, Wang L
Neuromuscul Disord
. 2020 Feb;
30(3):200-206.
PMID: 32057637
Inclusion body myositis (IBM) is a slowly progressive and heterogeneous disorder that is a challenge for measuring clinical trial efficacy. The current methods of measuring progression of the disease utilizes...
8.
Devalliere J, Chen Y, Dooley K, Yarmush M, Uygun B
Acta Biomater
. 2018 Aug;
78:151-164.
PMID: 30071351
Statement Of Significance: There is a critical need for novel organ replacement therapies as the grafts for transplantation fall short of demand. Recent advances in tissue engineering, through the use...
9.
Devalliere J, Dooley K, Hu Y, Kelangi S, Uygun B, Yarmush M
Biomaterials
. 2017 Jul;
141:149-160.
PMID: 28688286
Growth factor therapy is a promising approach for chronic diabetic wounds, but strategies to efficiently and cost-effectively deliver active molecules to the highly proteolytic wound environment remain as major obstacles....
10.
Bulutoglu B, Dooley K, Szilvay G, Blenner M, Banta S
ACS Synth Biol
. 2017 May;
6(9):1732-1741.
PMID: 28520402
Alternative scaffolds for biomolecular recognition are being developed to overcome some of the limitations associated with immunoglobulin domains. The repeat-in-toxin (RTX) domain is a repeat protein sequence that reversibly adopts...