Kevin Deng
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Explore the profile of Kevin Deng including associated specialties, affiliations and a list of published articles.
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10
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59
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Recent Articles
1.
Poznansky S, Yu M, Deng K, Fu Q, Markmann J, LeGuern C
Front Immunol
. 2023 May;
14:1173672.
PMID: 37180165
A subset of B-cells with tolerogenic functions, termed B-regulatory cells or Bregs, is characterized by the expression of anti-inflammatory/tolerogenic cytokines, namely IL-10, TGF-β, and IL-35, that contribute to their regulatory...
2.
Lee K, Fu Q, Huai G, Deng K, Lei J, Kojima L, et al.
JCI Insight
. 2022 Aug;
7(17).
PMID: 35943811
B lymphocytes have long been recognized for their critical contributions to adaptive immunity, providing defense against pathogens through cognate antigen presentation to T cells and Ab production. More recently appreciated...
3.
Matheson R, Deng K, Huai G, Lee K, Feeney N, Coe T, et al.
Transplant Rev (Orlando)
. 2021 Dec;
36(1):100674.
PMID: 34861509
Transplantation of xenogeneic organs is an attractive solution to the existing organ shortage dilemma, thus, securing a clinically acceptable prolongation of xenograft survival is an important goal. In preclinical transplantation...
4.
Fu Q, Lee K, Huai G, Deng K, Agarwal D, Rickert C, et al.
Am J Transplant
. 2021 Jul;
21(12):3847-3857.
PMID: 34327838
Regulatory B cells (Bregs) have shown promise as anti-rejection therapy applied to organ transplantation. However, less is known about their effect on other B cell populations that are involved in...
5.
Fu Q, Agarwal D, Deng K, Matheson R, Yang H, Wei L, et al.
Front Immunol
. 2021 Jul;
12:695806.
PMID: 34305931
Efforts at finding potential biomarkers of tolerance after kidney transplantation have been hindered by limited sample size, as well as the complicated mechanisms underlying tolerance and the potential risk of...
6.
Li L, Shi R, Gu J, Tung Y, Zhou Y, Zhou D, et al.
Acta Neuropathol Commun
. 2021 Feb;
9(1):28.
PMID: 33597014
Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer's disease (AD) and related tauopathies. Regional distribution of NFTs is associated with the progression of the disease...
7.
Tanimine N, Burrell B, Deng K, Rickert C, Lee K, Feeney N, et al.
J Immunol Methods
. 2021 Feb;
491:112987.
PMID: 33556344
Precise analyses of alloreactive T cell phenotype and function can inform both the nature and intensity of adaptive responses to transplant antigens. However, alloreactive T cells are sparse and difficult...
8.
Kimura S, Rickert C, Kojima L, Aburawi M, Tanimine N, Fontan F, et al.
Am J Transplant
. 2019 Dec;
20(4):977-987.
PMID: 31823520
Through multiple mechanisms, regulatory B cells (Breg) have been shown to play an important role in the development of allograft tolerance. However, a careful understanding of the role of antigen-specificity...
9.
Fu Q, Yang F, Liao M, Feeney N, Deng K, Serifis N, et al.
Front Oncol
. 2019 Aug;
9:737.
PMID: 31448237
Post-transplant (post-Tx) kidney cancer has become the second-highest cause of death in kidney recipients. Late diagnosis and treatment are the main reasons for high mortality. Further research into early diagnosis...
10.
Zhao X, Wang Y, Yu Y, Jiang H, Babinska A, Chen X, et al.
Thromb Haemost
. 2018 Nov;
118(12):2086-2097.
PMID: 30419596
It remains unclear whether plasma phospholipid transfer protein (PLTP) is involved in hyper-coagulation or hypo-coagulation. This study investigated the direct effect of PLTP on platelet aggregation and the underlying mechanism....