Rudy Matheson
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Explore the profile of Rudy Matheson including associated specialties, affiliations and a list of published articles.
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10
Citations
143
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Recent Articles
1.
Mojoudi M, Taggart M, Karadagi A, Hassan M, Tomosugi T, Tomofuji K, et al.
Xenotransplantation
. 2024 Aug;
31(4):e12879.
PMID: 39166818
Transplantation remains the preferred treatment for end-stage kidney disease but is critically limited by the number of available organs. Xenografts from genetically modified pigs have become a promising solution to...
2.
Anand R, Layer J, Heja D, Hirose T, Lassiter G, Firl D, et al.
Nature
. 2023 Oct;
622(7982):393-401.
PMID: 37821590
Recent human decedent model studies and compassionate xenograft use have explored the promise of porcine organs for human transplantation. To proceed to human studies, a clinically ready porcine donor must...
3.
Deng H, Zhang A, Pang D, Xi Y, Yang Z, Matheson R, et al.
Cell Rep Med
. 2023 Mar;
4(3):100959.
PMID: 36863336
The transplanting islets to the liver approach suffers from an immediate posttransplant loss of islets of more than 50%, progressive graft dysfunction over time, and precludes recovery of grafts should...
4.
Lu H, Ashiqueali R, Lin C, Walchale A, Clendaniel V, Matheson R, et al.
Mol Neurobiol
. 2022 Oct;
60(1):235-246.
PMID: 36258136
We have previously shown that selective inhibition of histone deacetylase 3 (HDAC3) decreases infarct volume and improves long-term functional outcomes after stroke. In this study, we examined the effects of...
5.
Matheson R, Deng K, Huai G, Lee K, Feeney N, Coe T, et al.
Transplant Rev (Orlando)
. 2021 Dec;
36(1):100674.
PMID: 34861509
Transplantation of xenogeneic organs is an attractive solution to the existing organ shortage dilemma, thus, securing a clinically acceptable prolongation of xenograft survival is an important goal. In preclinical transplantation...
6.
Ma D, Hirose T, Lassiter G, Sasaki H, Rosales I, Coe T, et al.
Am J Transplant
. 2021 Jul;
22(1):46-57.
PMID: 34331749
Porcine cells devoid of three major carbohydrate xenoantigens, αGal, Neu5GC, and SDa (TKO) exhibit markedly reduced binding of human natural antibodies. Therefore, it is anticipated that TKO pigs will be...
7.
Fu Q, Lee K, Huai G, Deng K, Agarwal D, Rickert C, et al.
Am J Transplant
. 2021 Jul;
21(12):3847-3857.
PMID: 34327838
Regulatory B cells (Bregs) have shown promise as anti-rejection therapy applied to organ transplantation. However, less is known about their effect on other B cell populations that are involved in...
8.
Fu Q, Agarwal D, Deng K, Matheson R, Yang H, Wei L, et al.
Front Immunol
. 2021 Jul;
12:695806.
PMID: 34305931
Efforts at finding potential biomarkers of tolerance after kidney transplantation have been hindered by limited sample size, as well as the complicated mechanisms underlying tolerance and the potential risk of...
9.
Serifis N, Matheson R, Cloonan D, Rickert C, Markmann J, Coe T
Front Surg
. 2021 Apr;
8:625394.
PMID: 33842530
Although efforts have been made by transplant centers to increase the pool of available livers by extending the criteria of liver acceptance, this practice creates risks for recipients that include...
10.
Matheson R, Chida K, Lu H, Clendaniel V, Fisher M, Thomas A, et al.
Transl Stroke Res
. 2020 Feb;
11(5):1052-1063.
PMID: 32016769
Histone deacetylase 3 (HDAC3) has been implicated as neurotoxic in several neurodegenerative conditions. However, the role of HDAC3 in ischemic stroke has not been thoroughly explored. We tested the hypothesis...