Kevin D Sarge
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Explore the profile of Kevin D Sarge including associated specialties, affiliations and a list of published articles.
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Citations
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Recent Articles
1.
Sarge K
Curr Protoc Protein Sci
. 2016 Feb;
83:14.8.1-14.8.8.
PMID: 26836406
Sumoylation, wherein small ubiquitin-like modifier (SUMO) proteins are covalently attached to specific lysine residues of target proteins, plays an important role in regulating many diverse cellular processes via its control...
2.
Gandhapudi S, Murapa P, Threlkeld Z, Ward M, Sarge K, Snow C, et al.
J Immunol
. 2013 Sep;
191(8):4068-79.
PMID: 24043900
Heat shock transcription factor 1 (HSF1) is a major transcriptional regulator of the heat shock response in eukaryotic cells. HSF1 is evoked in response to a variety of cellular stressors,...
3.
Sarge K, Park-Sarge O
Biochimie
. 2012 Oct;
PMID: 23022145
This review has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can...
4.
Sarge K, Park-Sarge O
Int Rev Cell Mol Biol
. 2011 Apr;
288:167-83.
PMID: 21482412
The covalent attachment of small ubiquition-like modifier (SUMO) polypeptides, or sumoylation, is an important regulator of the functional properties of many proteins. Among these are many proteins implicated in human...
5.
Xing H, Hong Y, Sarge K
Cell Stress Chaperones
. 2009 Sep;
15(3):301-8.
PMID: 19768582
Cullin-RING ubiquitin ligases promote the polyubiquitination and degradation of many important cellular proteins, which previous studies indicated can be targeted for degradation via interaction with BTB domain-containing subunits of this...
6.
Sarge K, Park-Sarge O
Methods Mol Biol
. 2009 Sep;
590:265-77.
PMID: 19763510
Small ubiquitin-related modifier (SUMO) is an ubiquitin-like protein that is covalently attached to a variety of target proteins. Unlike ubiquitination, sumoylation does not target proteins for proteolytic breakdown, but is...
7.
Sarge K, Xing H, Park-Sarge O
Methods Mol Biol
. 2009 Sep;
590:223-33.
PMID: 19763507
In order to fully understand the functions of a DNA-binding protein it is necessary to identify all of its binding sites in chromosomes and assess the role of each site...
8.
Wilkerson D, Sarge K
Reproduction
. 2009 Apr;
137(6):923-9.
PMID: 19336471
The Hspa1b (Hsp70.1) gene is one of the first genes expressed after fertilization, with expression occurring during the minor zygotic genome activation (ZGA) in the absence of stress. This expression...
9.
Sarge K, Park-Sarge O
Trends Biochem Sci
. 2009 Mar;
34(4):200-5.
PMID: 19282183
Covalent modification by SUMO polypeptides, or sumoylation, is an important regulator of the functional properties of many proteins. Among these are several proteins implicated in human diseases including cancer, Huntington's,...
10.
Zhang J, Sarge K
FEBS Lett
. 2009 Feb;
583(6):960-4.
PMID: 19233177
Bmi-1 is a polycomb protein that plays an important role in tumor cell development and maintaining stem cell populations of many cell lineages. Here we identify a polymorphism in human...