Keti Bardhi
Overview
Explore the profile of Keti Bardhi including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
53
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0
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Recent Articles
1.
Coates S, Bardhi K, Prasad B, Lazarus P
Pharmaceutics
. 2025 Jan;
16(12.
PMID: 39771577
Morphine is a commonly prescribed opioid analgesic used to treat chronic pain. Morphine undergoes glucuronidation by UDP-glucuronosyltransferase (UGT) 2B7 to form morphine-3-glucuronide and morphine-6-glucuronide. Morphine is the gold standard for...
2.
Coates S, Bardhi K, Lazarus P
Pharmaceutics
. 2024 Mar;
16(3).
PMID: 38543313
Opioids are commonly prescribed for the treatment of chronic pain. Approximately 50% of adults who are prescribed opioids for pain co-use cannabis with their opioid treatment. Morphine is primarily metabolized...
3.
Bardhi K, Coates S, Chen G, Lazarus P
Pharmaceutics
. 2024 Feb;
16(2).
PMID: 38399297
Benzodiazepines (BZDs) such as oxazepam are commonly prescribed depressant drugs known for their anxiolytic, hypnotic, muscle relaxant, and anticonvulsant effects and are frequently used in conjunction with other illicit drugs...
4.
Perez-Pouchoulen M, Jaiyesimi A, Bardhi K, Waddell J, Banerjee A
Pediatr Res
. 2023 Feb;
94(2):539-546.
PMID: 36810641
Background: Hypoxic ischemic encephalopathy remains a significant cause of developmental disability. The standard of care for term infants is hypothermia, which has multifactorial effects. Therapeutic hypothermia upregulates the cold-inducible protein...
5.
Nasrin S, Coates S, Bardhi K, Watson C, Muscat J, Lazarus P
Chem Res Toxicol
. 2023 Jan;
36(2):177-187.
PMID: 36626330
Cannabis-based products have experienced notable increases in co-usage alongside tobacco products. Several cannabinoids exhibit inhibition of a number of cytochrome P450 (CYP) and UDP glucuronosyltransferase (UGT) enzymes, but few studies...
6.
Bardhi K, Coates S, Watson C, Lazarus P
Expert Rev Clin Pharmacol
. 2022 Nov;
15(12):1443-1460.
PMID: 36384377
Introduction: Cannabis is an increasingly popular recreational and medicinal drug in the USA. While cannabis is still a Schedule 1 drug federally, many states have lifted the ban on its...
7.
Nasrin S, Watson C, Bardhi K, Fort G, Chen G, Lazarus P
Drug Metab Dispos
. 2021 Sep;
49(12):1081-1089.
PMID: 34493601
The UDP-glucuronosyltransferase (UGT) family of enzymes play a central role in the metabolism and detoxification of a wide range of endogenous and exogenous compounds. UGTs exhibit a high degree of...
8.
Kight K, Argue K, Bumgardner J, Bardhi K, Waddell J, McCarthy M
Behav Neurosci
. 2021 Jul;
135(6):782-803.
PMID: 34323517
Loss-of-function mutations in the synaptic protein neurexin1α (NRXN1α) are associated with several neurodevelopmental disorders, including autism spectrum disorder (ASD), schizophrenia, and attention-deficit hyperactivity disorder (ADHD), and many of these disorders...
9.
McKay T, Hart K, Horn A, Kessler H, Dodge G, Bardhi K, et al.
J Struct Funct Genomics
. 2015 Jan;
16(1):43-54.
PMID: 25630330
Working with a combination of ProMOL (a plugin for PyMOL that searches a library of enzymatic motifs for local structural homologs), BLAST and Pfam (servers that identify global sequence homologs),...