Kerstin Huebner
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Explore the profile of Kerstin Huebner including associated specialties, affiliations and a list of published articles.
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9
Citations
78
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Recent Articles
1.
Wimmers D, Huebner K, Dale T, Papargyriou A, Reichert M, Hartmann A, et al.
Pathol Res Pract
. 2025 Mar;
269:155890.
PMID: 40073643
Intestinal organoids reflect the 3D structure and function of their original tissues. Organoid are typically cultured in Matrigel, an extracellular matrix (ECM) mimicking the basement membrane, which is suitable for...
2.
Gulec Taskiran A, Husnugil H, Soltani Z, Oral G, Menemenli N, Hampel C, et al.
Traffic
. 2024 Sep;
25(9):e12956.
PMID: 39313937
Limited nutrient availability in the tumor microenvironment can cause the rewiring of signaling and metabolic networks to confer cancer cells with survival advantages. We show here that the limitation of...
3.
Pastorino G, Sheraj I, Huebner K, Ferrero G, Kunze P, Hartmann A, et al.
J Pathol
. 2024 Jan;
262(3):347-361.
PMID: 38235615
Partial epithelial-mesenchymal transition (p-EMT) has recently been identified as a hybrid state consisting of cells with both epithelial and mesenchymal characteristics and is associated with the migration, metastasis, and chemoresistance...
4.
Yang H, Huebner K, Hampel C, Erlenbach-Wuensch K, Selvamani S, Shukla V, et al.
BMC Cancer
. 2023 May;
23(1):480.
PMID: 37237279
Background: The role of ATF2 in colon cancer (CC) is controversial. Recently, we reported that low ATF2 expression is characteristic of highly invasive tumors, suggesting that ATF2 might also be...
5.
ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2
Huebner K, Erlenbach-Wuensch K, Prochazka J, Sheraj I, Hampel C, Mrazkova B, et al.
Cell Mol Life Sci
. 2022 Jul;
79(8):423.
PMID: 35838828
In cancer, the activating transcription factor 2 (ATF2) has pleiotropic functions in cellular responses to growth stimuli, damage, or inflammation. Due to only limited studies, the significance of ATF2 in...
6.
Bueno-Fortes S, Muenzner J, Berral-Gonzalez A, Hampel C, Lindner P, Berninger A, et al.
Cancers (Basel)
. 2022 Jan;
14(1).
PMID: 35008299
The epithelial-mesenchymal transition (EMT) is associated with tumor aggressiveness and increased invasion, migration, metastasis, angiogenesis, and drug resistance. Although the HCT116 p21-/- cell line is well known for its EMT-associated...
7.
Schreyer L, Mittermeier C, Franz M, Meier M, Martin D, Maier K, et al.
Cancers (Basel)
. 2021 Nov;
13(21).
PMID: 34771537
Human hepatocellular carcinoma (HCC) is among the most lethal and common cancers in the human population, and new molecular targets for therapeutic intervention are urgently needed. Deleted in liver cancer...
8.
Huebner K, Prochazka J, Monteiro A, Mahadevan V, Schneider-Stock R
Mutagenesis
. 2019 Dec;
34(5-6):375-389.
PMID: 31799611
In contrast to the continuous increase in survival rates for many cancer entities, colorectal cancer (CRC) and pancreatic cancer are predicted to be ranked among the top 3 cancer-related deaths...
9.
Ndreshkjana B, Capci A, Klein V, Chanvorachote P, Muenzner J, Huebner K, et al.
Cell Death Dis
. 2019 May;
10(6):379.
PMID: 31097715
Cancer stem cells (CSCs) residing in colorectal cancer tissues have tumorigenic capacity and contribute to chemotherapeutic resistance and disease relapse. It is well known that the survival of colorectal CSCs...
10.
Steinmann S, Gali-Muhtasib H, Huebner K, Al-Halabi R, Abou Merhi R, Aman P, et al.
Cancer Lett
. 2015 Jul;
367(2):147-56.
PMID: 26225840
Liposarcoma is one of the most common soft tissue sarcomas in adults. Recognized histological subtypes include well differentiated/dedifferentiated liposarcoma (WD/DDLS), myxoid liposarcoma (MLS) and pleomorphic liposarcoma. Currently, there are no...