Kento Onishi
Overview
Explore the profile of Kento Onishi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
342
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yachie-Kinoshita A, Onishi K, Ostblom J, Langley M, Posfai E, Rossant J, et al.
Mol Syst Biol
. 2018 Jan;
14(1):e7952.
PMID: 29378814
Pluripotent stem cells (PSCs) exist in multiple stable states, each with specific cellular properties and molecular signatures. The mechanisms that maintain pluripotency, or that cause its destabilization to initiate development,...
2.
Curtis A, Li D, Deveale B, Onishi K, Kim M, Blelloch R, et al.
Integr Biol (Camb)
. 2016 Dec;
9(1):50-57.
PMID: 28001149
Micropatterned cocultures are a useful experimental tool for the study of cell-cell interactions. Patterning methods often rely on sequential seeding of different cell types or removal of a barrier separating...
3.
Okude J, Ueda T, Kofuku Y, Sato M, Nobuyama N, Kondo K, et al.
Angew Chem Int Ed Engl
. 2015 Nov;
54(52):15771-6.
PMID: 26568421
G-protein-coupled receptor (GPCR) ligands impart differing degrees of signaling in the G-protein and arrestin pathways, in phenomena called "biased signaling". However, the mechanism underlying the biased signaling of GPCRs is...
4.
Onishi K, Zandstra P
Development
. 2015 Jul;
142(13):2230-6.
PMID: 26130754
Leukemia inhibitory factor (LIF) is a member of the interleukin-6 (IL-6) cytokine family. All members of this family activate signal transducer and activator of transcription 3 (STAT3), a transcription factor...
5.
Onishi K, Tonge P, Nagy A, Zandstra P
Stem Cell Reports
. 2014 Jul;
3(1):156-68.
PMID: 25068129
Conversion of EpiSCs to naive ESCs is a rare event that is driven by the reestablishment of the naive transcription factor network. In mice, STAT3 activation is sufficient to drive...
6.
Deveale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, et al.
PLoS Genet
. 2013 Nov;
9(11):e1003957.
PMID: 24244203
Oct4 is a widely recognized pluripotency factor as it maintains Embryonic Stem (ES) cells in a pluripotent state, and, in vivo, prevents the inner cell mass (ICM) in murine embryos...
7.
Onishi K, Tonge P, Nagy A, Zandstra P
Integr Biol (Camb)
. 2012 Sep;
4(11):1367-76.
PMID: 22990140
Embryonic stem cells (ESC) and epiblast stem cells (EpiSC) are distinct pluripotent stem cell states that require different signaling pathways for their self-renewal. Forward transitions between ESC and EpiSC can...
8.
Moledina F, Clarke G, Oskooei A, Onishi K, Gunther A, Zandstra P
Proc Natl Acad Sci U S A
. 2012 Feb;
109(9):3264-9.
PMID: 22334649
Local (cell-level) signaling environments, regulated by autocrine and paracrine signaling, and modulated by cell organization, are hypothesized to be fundamental stem cell fate control mechanisms used during development. It has,...
9.
Hewel J, Liu J, Onishi K, Fong V, Chandran S, Olsen J, et al.
Mol Cell Proteomics
. 2010 May;
9(11):2460-73.
PMID: 20467045
Effective methods to detect and quantify functionally linked regulatory proteins in complex biological samples are essential for investigating mammalian signaling pathways. Traditional immunoassays depend on proprietary reagents that are difficult...
10.
Peerani R, Onishi K, Mahdavi A, Kumacheva E, Zandstra P
PLoS One
. 2009 Aug;
4(7):e6438.
PMID: 19649273
In vivo, stem cell fate is regulated by local microenvironmental parameters. Governing parameters in this stem cell niche include soluble factors, extra-cellular matrix, and cell-cell interactions. The complexity of this...