Jonathan B Olsen
Overview
Explore the profile of Jonathan B Olsen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
1385
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dowless M, Lowery C, Shackleford T, Renschler M, Stephens J, Flack R, et al.
Clin Cancer Res
. 2018 Aug;
24(23):6028-6039.
PMID: 30131386
Purpose: Ewing sarcoma (ES) is a rare and highly malignant cancer that occurs in the bone and surrounding tissue of children and adolescents. The fusion transcription factor that drives ES...
2.
Deimling S, Olsen J, Tropepe V
Neurogenesis (Austin)
. 2017 Jun;
4(1):e1316888.
PMID: 28596979
Epigenetic regulators play a crucial role in neurodevelopment. One such epigenetic complex, Ehmt1/2 (G9a/GLP), is essential for repressing gene transcription by methylating H3K9 in a highly tissue- and temporal-specific manner....
3.
Olsen J, Wong L, Deimling S, Miles A, Guo H, Li Y, et al.
Stem Cell Reports
. 2016 Aug;
7(3):454-470.
PMID: 27546533
Proliferating progenitor cells undergo changes in competence to give rise to post-mitotic progeny of specialized function. These cell-fate transitions typically involve dynamic regulation of gene expression by histone methyltransferase (HMT)...
4.
Olsen J, Cao X, Han B, Chen L, Horvath A, Richardson T, et al.
Mol Cell Proteomics
. 2016 Jan;
15(3):892-905.
PMID: 26750096
The significance of non-histone lysine methylation in cell biology and human disease is an emerging area of research exploration. The development of small molecule inhibitors that selectively and potently target...
5.
Cassar P, Carpenedo R, Samavarchi-Tehrani P, Olsen J, Park C, Chang W, et al.
EMBO Rep
. 2015 Aug;
16(10):1334-57.
PMID: 26265008
In embryonic stem cells (ESCs), gene regulatory networks (GRNs) coordinate gene expression to maintain ESC identity; however, the complete repertoire of factors regulating the ESC state is not fully understood....
6.
Marcon E, Jain H, Bhattacharya A, Guo H, Phanse S, Pu S, et al.
Nat Methods
. 2015 Jun;
12(8):725-31.
PMID: 26121405
Antibodies are used in multiple cell biology applications, but there are no standardized methods to assess antibody quality-an absence that risks data integrity and reproducibility. We describe a mass spectrometry-based...
7.
Nguyen H, Allali-Hassani A, Antonysamy S, Chang S, Chen L, Curtis C, et al.
J Biol Chem
. 2015 Apr;
290(22):13641-53.
PMID: 25825497
SMYD2 is a lysine methyltransferase that catalyzes the monomethylation of several protein substrates including p53. SMYD2 is overexpressed in a significant percentage of esophageal squamous primary carcinomas, and that overexpression...
8.
Salvi J, Chan J, Szafranski K, Liu T, Wu J, Olsen J, et al.
Dev Cell
. 2014 Jul;
30(2):177-91.
PMID: 25073155
Intergenic transcription within repetitive loci such as the ribosomal DNA (rDNA) repeats of yeast commonly triggers aberrant recombination. Major mechanisms suppressing aberrant rDNA recombination rely on chromatin silencing or RNAPII...
9.
RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation
Ni Z, Xu C, Guo X, Hunter G, Kuznetsova O, Tempel W, et al.
Nat Struct Mol Biol
. 2014 Jul;
21(8):686-695.
PMID: 24997600
The RNA polymerase II (RNAPII) C-terminal domain (CTD) heptapeptide repeats (1-YSPTSPS-7) undergo dynamic phosphorylation and dephosphorylation during the transcription cycle to recruit factors that regulate transcription, RNA processing and chromatin...
10.
Marcon E, Ni Z, Pu S, Turinsky A, Trimble S, Olsen J, et al.
Cell Rep
. 2014 Jul;
8(1):297-310.
PMID: 24981860
Chromatin regulation is driven by multicomponent protein complexes, which form functional modules. Deciphering the components of these modules and their interactions is central to understanding the molecular pathways these proteins...