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Kent Lundholm

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Articles 64
Citations 1127
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Recent Articles
1.
Iresjo B, Smedh U, Engstrom C, Persson J, Martensson C, Lundholm K
J Transl Med . 2024 Jul; 22(1):675. PMID: 39039509
Background: Effects of preoperative drinks on muscle metabolism are unclear despite general recommendations. The aim of the present study was therefore to compare metabolic effects of a preoperative oral nutrition...
2.
Iresjo B, Blomstrom S, Engstrom C, Johnsson E, Lundholm K
Surgery . 2024 Jan; 175(4):929-935. PMID: 38218686
Background: Antibiotic treatment of unselected patients with acute appendicitis is safe and effective. However, it is unknown to what extent early provision of antibiotic treatment may represent overtreatment due to...
3.
Iresjo B, Kir S, Lundholm K
Transl Oncol . 2023 Aug; 36:101752. PMID: 37540958
Background: Cancer-cachexia is a complex syndrome secondary to physiological mechanisms related to classical hormone and immune alterations, where contributions of neuro-endocrine involvement have been less evaluated. Therefore, the aim of...
4.
Iresjo B, Diep L, Lundholm K
PLoS One . 2022 Jul; 17(7):e0270927. PMID: 35802556
Background: IGF-1 is considered an important regulator of muscle protein synthesis. However, its role in stimulation of muscle protein synthesis by amino acids (AA) is not clear, despite pronounced alterations...
5.
Khan M, Engstrom C, Bourghardt Fagman J, Smedh U, Lundholm K, Iresjo B
Oncol Rep . 2022 May; 47(6). PMID: 35543149
Inflammatory signaling through prostaglandin E2 receptor subtype 2 (EP2) is associated with malignant tumor growth in both experimental models and cancer patients. Thus, the absence of EP2 receptors in host...
6.
Iresjo B, Landin A, Ohlsson C, Lundholm K
Genes Nutr . 2019 Nov; 14:29. PMID: 31741685
Background: Previous investigations have indicated upregulation of gene expression in cellular pathways related to the biosynthesis of steroids in response to amino acids (AA) in skeletal muscle cells. This suggests...
7.
Bourghardt Fagman J, Ljungman D, Falk P, Iresjo B, Engstrom C, Naredi P, et al.
Oncol Lett . 2019 Jun; 17(6):5361-5368. PMID: 31186753
The effects of EGFR and COX-2 protein overexpression on clinical outcomes in pancreatic ductal adenocarcinoma (PDAC) patients remains unclear. Therefore, the aim of the present study was to evaluate the...
8.
Purcell S, Wallengren O, Baracos V, Lundholm K, Iresjo B, Chu Q, et al.
Clin Nutr . 2019 Apr; 39(1):134-140. PMID: 30975554
Background & Aims: Resting energy expenditure (REE) is variable in cancer and might be influenced by changes in tumor burden, systemic inflammation, and body composition. The objective of this study...
9.
Vilhav C, Engstrom C, Naredi P, Novotny A, Bourghardt-Fagman J, Iresjo B, et al.
Oncol Lett . 2018 Nov; 16(5):6331-6338. PMID: 30405768
Circulating tumor cells (CTCs) are able to predict outcome in patients with breast, colon and prostate cancer and appear to be promising biomarkers of pancreatic carcinoma. The aim of the...
10.
Iresjo B, Engstrom C, Smedh U, Lundholm K
JPEN J Parenter Enteral Nutr . 2018 Oct; 43(4):497-507. PMID: 30350380
Background: Evaluation of improvements by nutrition support to severely ill patients requires sensitive methods to demonstrate activation of protein synthesis in various tissues from groups with a limited number of...