Kenneth Robzyk
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Explore the profile of Kenneth Robzyk including associated specialties, affiliations and a list of published articles.
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7
Citations
386
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Recent Articles
1.
Werr L, Bartenhagen C, Rosswog C, Cartolano M, Voegele C, Sexton-Oates A, et al.
J Clin Oncol
. 2024 Sep;
43(2):214-225.
PMID: 39348606
Purpose: The clinical course of pulmonary carcinoids ranges from indolent to fatal disease, suggesting that specific molecular alterations drive progression toward the fully malignant state. A similar spectrum of clinical...
2.
Yan P, Patel H, Sharma S, Corben A, Wang T, Panchal P, et al.
Cell Rep
. 2020 Jul;
31(13):107840.
PMID: 32610141
Stresses associated with disease may pathologically remodel the proteome by both increasing interaction strength and altering interaction partners, resulting in proteome-wide connectivity dysfunctions. Chaperones play an important role in these...
3.
Laddha S, da Silva E, Robzyk K, Untch B, Ke H, Rekhtman N, et al.
Cancer Res
. 2019 Jul;
79(17):4339-4347.
PMID: 31300474
Lung carcinoids (LC) are rare and slow growing primary lung neuroendocrine tumors. We performed targeted exome sequencing, mRNA sequencing, and DNA methylation array analysis on macro-dissected LCs. Recurrent mutations were...
4.
Choi S, Wang D, Chen X, Tang L, Verma A, Chen Z, et al.
Mol Cancer
. 2019 May;
18(1):92.
PMID: 31072393
The receptor for hyaluronic acid-mediated motility (RHAMM) is upregulated in various cancers. We previously screened genes upregulated in human hepatocellular carcinomas for their metastatic function in a mouse model of...
5.
Chan C, Laddha S, Lewis P, Koletsky M, Robzyk K, da Silva E, et al.
Nat Commun
. 2018 Oct;
9(1):4158.
PMID: 30315258
The commonly mutated genes in pancreatic neuroendocrine tumors (PanNETs) are ATRX, DAXX, and MEN1. We genotyped 64 PanNETs and found 58% carry ATRX, DAXX, and MEN1 mutations (A-D-M mutant PanNETs)...
6.
Robzyk K, Oen H, Buchanan G, Butler L, Tilley W, Mandal A, et al.
Mol Cell Endocrinol
. 2007 Mar;
268(1-2):67-74.
PMID: 17336451
The mechanisms underlying androgen receptor (AR)-mediated progression of prostate cancer following androgen ablation have yet to be fully determined. On this basis we screened naturally occurring mutants of human AR...
7.
Scroggins B, Robzyk K, Wang D, Marcu M, Tsutsumi S, Beebe K, et al.
Mol Cell
. 2007 Jan;
25(1):151-9.
PMID: 17218278
Heat-shock protein 90 (Hsp90) chaperones a key subset of signaling proteins and is necessary for malignant transformation. Hsp90 is subject to an array of posttranslational modifications that affect its function,...