Kenneth P LeClair
Overview
Explore the profile of Kenneth P LeClair including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
141
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0
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Recent Articles
1.
Im J, Yu K, Illarionov P, LeClair K, Storey J, Kennedy M, et al.
J Biol Chem
. 2003 Oct;
279(1):299-310.
PMID: 14551186
CD1 proteins are antigen-presenting molecules that bind foreign and self-lipids and stimulate specific T cell responses. In the current study, we investigated ligand binding by CD1 proteins by developing a...
2.
Dascher C, Hiromatsu K, Xiong X, Morehouse C, Watts G, Liu G, et al.
Int Immunol
. 2003 Jul;
15(8):915-25.
PMID: 12882829
Lipids and glycolipid molecules derived from Mycobacterium tuberculosis can be presented to T cells by CD1 cell-surface molecules in humans. These lipid-specific T cells are cytolytic, secrete pro-inflammatory cytokines and...
3.
Hiromatsu K, Dascher C, LeClair K, Sugita M, Furlong S, Brenner M, et al.
J Immunol
. 2002 Jun;
169(1):330-9.
PMID: 12077262
Group 1 CD1 molecules have been shown to present lipid and glycolipid Ags of mycobacteria to human T cells. However, a suitable animal model for the investigation of this component...
4.
Hiromatsu K, Dascher C, Sugita M, Behar S, LeClair K, Brenner M, et al.
Immunology
. 2002 Jun;
106(2):159-72.
PMID: 12047745
CD1 molecules are cell-surface glycoproteins with strong structural similarities to major histocompatibility complex (MHC) class I molecules, and studies in humans and mice have demonstrated that CD1 proteins perform the...