Kenneth J Ritchie
Overview
Explore the profile of Kenneth J Ritchie including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
834
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Recent Articles
1.
Guetchueng S, Nahar L, Ritchie K, Sarker S
Eur J Cancer Prev
. 2021 Dec;
31(1):50-53.
PMID: 34871198
The cancer chemopreventive potential of various solvent extracts from six medicinal plants was evaluated by their ability to activate the transcription factor Nrf2 using AREc32 cells, which contain a luciferase...
2.
Popoola T, Guetchueng S, Ritchie K, Awodele O, Dempster N, Akinloye O, et al.
BMC Complement Med Ther
. 2021 Sep;
21(1):234.
PMID: 34537049
Background: Uvaria chamae (UC) and Olax subscorpioidea (OS) roots are included in traditional anti-cancer remedies and some studies have identified their chemopreventive/chemotherapeutic potential. This study aimed to identify some cellular/molecular...
3.
Jasim H, Nahar L, Jasim M, Moore S, Ritchie K, Sarker S
Biomolecules
. 2021 Aug;
11(8).
PMID: 34439870
Chalcones belong to the flavonoid class of phenolic compounds. They form one of the largest groups of bioactive natural products. The potential anticancer, anti-inflammatory, antimicrobial, antioxidant, and antiparasitic properties of...
4.
Radapong S, Chan K, Sarker S, Ritchie K
Front Pharmacol
. 2021 Jul;
12:694562.
PMID: 34305605
Oxyresveratrol (OXY) is a small molecule phytochemical which has been reported to have important biological function. The aim of this study was to elucidate the gene expression and biological pathways...
5.
Radapong S, Sarker S, Ritchie K
Molecules
. 2020 Jun;
25(11).
PMID: 32492964
Wall. ex Roxb. (family: ) has been used as a traditional Thai medicine for the treatment of various parasitic diseases. This species has been reported to be the source of...
6.
Basar N, Nahar L, Oridupa O, Ritchie K, Talukdar A, Stafford A, et al.
Phytochem Anal
. 2016 Aug;
27(5):233-8.
PMID: 27527356
Introduction: Nuclear factor (erythroid-derived 2)-like factor 2 (Nrf2) is a transcription factor that regulates expression of many detoxification enzymes. Nrf2-antioxidant responsive element (Nrf2-ARE) signalling pathway can be a target for...
7.
Basar N, Oridupa O, Ritchie K, Nahar L, Osman N, Stafford A, et al.
Phytother Res
. 2015 Mar;
29(6):944-8.
PMID: 25779384
Glycyrrhiza glabra L. (Fabaceae), commonly known as 'liquorice', is a well-known medicinal plant. Roots of this plant have long been used as a sweetening and flavouring agent in food and...
8.
Henderson C, Ritchie K, McLaren A, Chakravarty P, Wolf C
Cancer Res
. 2011 Oct;
71(22):7048-60.
PMID: 21975931
The glutathione S-transferase GSTP is overexpressed in many human cancers and chemotherapy-resistant cancer cells, where there is evidence that GSTP may have additional functions beyond its known catalytic role. On...
9.
Ritchie K, Walsh S, Sansom O, Henderson C, Wolf C
Proc Natl Acad Sci U S A
. 2009 Nov;
106(49):20859-64.
PMID: 19915149
Glutathione transferases are a multigene family of proteins that catalyze the conjugation of toxic electrophiles and carcinogens to glutathione. Glutathione transferase Pi (GSTP) is commonly overexpressed in human tumors and...
10.
Ritchie K, Henderson C, Wang X, Vassieva O, Carrie D, Farmer P, et al.
Cancer Res
. 2007 Oct;
67(19):9248-57.
PMID: 17909032
Human cancer is controlled by a complex interaction between genetic and environmental factors. Such environmental factors are well defined for smoking-induced lung cancer; however, the roles of specific genes have...