Kenneth H Grabstein
Overview
Explore the profile of Kenneth H Grabstein including associated specialties, affiliations and a list of published articles.
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8
Citations
876
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Recent Articles
1.
VanBrunt M, Shanebeck K, Caldwell Z, Johnson J, Thompson P, Martin T, et al.
Bioconjug Chem
. 2015 Sep;
26(11):2249-60.
PMID: 26332743
Antibody-drug conjugates (ADC) have emerged as potent antitumor drugs that provide increased efficacy, specificity, and tolerability over chemotherapy for the treatment of cancer. ADCs generated by targeting cysteines and lysines...
2.
Stenderup K, Rosada C, Shanebeck K, Brady W, Van Brunt M, King G, et al.
Protein Eng Des Sel
. 2015 Aug;
28(10):467-80.
PMID: 26271488
Targeting more than one molecule in multifactorial diseases involving several disease mediators may provide improved therapeutic efficacy. Psoriasis is a multifactorial disease in which interleukin (IL)-6 and IL-23 are important...
3.
Sylwester A, Mitchell B, Edgar J, Taormina C, Pelte C, Ruchti F, et al.
J Exp Med
. 2005 Sep;
202(5):673-85.
PMID: 16147978
Human cytomegalovirus (HCMV) infections of immunocompetent hosts are characterized by a dynamic, life-long interaction in which host immune responses, particularly of T cells, restrain viral replication and prevent disease but...
4.
Gervassi A, Alderson M, Suchland R, Maisonneuve J, Grabstein K, Probst P
Infect Immun
. 2004 Nov;
72(12):7231-9.
PMID: 15557648
Chlamydia trachomatis is an obligate intracellular gram-negative bacterium responsible for a wide spectrum of diseases in humans. Both genital and ocular C. trachomatis infections are associated with tissue inflammation and...
5.
Gervassi A, Grabstein K, Probst P, Hess B, Alderson M, Fling S
J Immunol
. 2004 Nov;
173(11):6905-13.
PMID: 15557186
The intracellular bacterial pathogen Chlamydia is sequestered from the host cell cytoplasm by remaining within an inclusion body during its replication cycle. Nevertheless, CD8(+) T cells recognizing Chlamydia Ags in...
6.
Gervassi A, Probst P, Stamm W, Marrazzo J, Grabstein K, Alderson M
J Immunol
. 2003 Oct;
171(8):4278-86.
PMID: 14530352
CD8(+) T cells are a key immune component for the eradication of many intracellular pathogens. This study aims to characterize the human CD8(+) T cell response to naturally processed chlamydial...
7.
Day F, Zhang Y, Clair P, Grabstein K, Mazel M, Rees A, et al.
J Immunol
. 2003 Jan;
170(3):1498-503.
PMID: 12538713
Linear peptides (SynB vectors) with specific sequence motifs have been identified that are capable of enhancing the transport of a wide range of molecules into cells. These peptide vectors have...
8.
Murray J, Gillogly M, Przepiorka D, Brewer H, Ibrahim N, Booser D, et al.
Clin Cancer Res
. 2002 Nov;
8(11):3407-18.
PMID: 12429628
To determine the toxicity and immunogenicity of the HER-2/neu, HLA-A2-restricted peptide E75 in patients with metastatic breast and ovarian cancer, 14 patients were vaccinated with escalating amounts of E75 (100,...