Kenjiro Yoshimura
Overview
Explore the profile of Kenjiro Yoshimura including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
508
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Recent Articles
11.
Saegusa Y, Yoshimura K
Cytoskeleton (Hoboken)
. 2015 Aug;
72(8):412-21.
PMID: 26257199
The motility of cilia and flagella of eukaryotic cells is controlled by second messengers such as Ca(2+), cAMP, and cGMP. In this study, the cAMP-dependent control of flagellar bending of...
12.
Ando C, Liu N, Yoshimura K
J Biochem
. 2015 Feb;
158(2):109-14.
PMID: 25697390
Many membrane proteins such as ion channels are oligomers, but the determinants of the degree of oligomerization are not fully understood. Mechanosensitive channel with large conductance (MscL), which is ubiquitous...
13.
Rowe I, Anishkin A, Kamaraju K, Yoshimura K, Sukharev S
J Gen Physiol
. 2014 Apr;
143(5):543-57.
PMID: 24778428
Cells actively regulate the macromolecular excluded volume of the cytoplasm to maintain the reciprocal fraction of free aqueous solution that is optimal for intracellular processes. However, the mechanisms whereby cells...
14.
Nakayama Y, Yoshimura K, Iida H
Biophys J
. 2013 Sep;
105(6):1366-75.
PMID: 24047987
Corynebacterium glutamicum MscCG, also referred to as NCgl1221, exports glutamate when biotin is limited in the culture medium. MscCG is a homolog of Escherichia coli MscS, which serves as an...
15.
Nakayama Y, Yoshimura K, Iida H
Nat Commun
. 2012 Aug;
3:1020.
PMID: 22910366
A key molecule of sensing machineries essential for survival upon hypo-osmotic shock is the mechanosensitive channel. The bacterial mechanosensitive channel MscS functions directly for this purpose by releasing cytoplasmic solutes...
16.
Nakayama Y, Yoshimura K, Iida H
Appl Environ Microbiol
. 2012 May;
78(15):5432-4.
PMID: 22610427
The A-to-V mutation at position 111 (A111V) in the mechanosensitive channel NCgl1221 (MscCG) causes constitutive glutamate secretion in Corynebacterium glutamicum. Patch clamp experiments revealed that NCgl1221 (A111V) had a significantly...
17.
Fujiu K, Nakayama Y, Iida H, Sokabe M, Yoshimura K
Nat Cell Biol
. 2011 Apr;
13(5):630-2.
PMID: 21478860
Ciliates and flagellates temporarily swim backwards on collision by generating a mechanoreceptor potential. Although this potential has been shown to be associated with cilia in Paramecium, the molecular entity of...
18.
Yoshimura K, Sokabe M
J R Soc Interface
. 2010 Apr;
7 Suppl 3:S307-20.
PMID: 20356872
Ion channels form a group of membrane proteins that pass ions through a pore beyond the energy barrier of the lipid bilayer. The structure of the transmembrane segment of membrane...
19.
Fujiu K, Nakayama Y, Yanagisawa A, Sokabe M, Yoshimura K
Curr Biol
. 2009 Jan;
19(2):133-9.
PMID: 19167228
Cilia and flagella can alter their beating patterns through changes in membrane excitation mediated by Ca(2+) influx. The ion channel that generates this Ca(2+) influx and its cellular distribution have...
20.
Yoshimura K, Usukura J, Sokabe M
Proc Natl Acad Sci U S A
. 2008 Mar;
105(10):4033-8.
PMID: 18310324
Bacterial cells avoid lysis in response to hypoosmotic shock through the opening of the mechanosensitive channel MscL. Upon channel opening, MscL is thought to expand in the plane of the...