Kenichi Nagase
Overview
Explore the profile of Kenichi Nagase including associated specialties, affiliations and a list of published articles.
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Articles
81
Citations
810
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Recent Articles
1.
Nagase K, Watanabe M, Kikuchi A, Okano T
Biomater Sci
. 2025 Feb;
PMID: 39996321
Various cell sheets have been used as effective and useful cellular tissues in tissue engineering and regenerative therapy. Poly(-isopropylacrylamide) (PNIPAAm)-modified surfaces have been investigated for effective cell sheet preparation. In...
2.
Nagase K, Suzuki S, Kanazawa H
Heliyon
. 2024 Aug;
10(15):e34668.
PMID: 39161811
Thermoresponsive polymer brushes have attracted considerable research attention owing to their unique properties. Herein, we developed silica beads grafted with poly(-isopropylacrylamide (NIPAAm)--3-acrylamidopropyl trimethylammonium chloride (APTAC)---butyl acrylamide (tBAAm) and P(NIPAAm--APTAC---butyl methacrylate(nBMA))...
3.
Nakao M, Nagase K
Regen Ther
. 2024 Jun;
26:80-88.
PMID: 38841206
Introduction: Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are promising candidates for stem cell therapy. Various methods such as enzymatic treatment, cell scraping, and temperature reduction using temperature-responsive cell culture...
4.
Hirotani T, Nagase K
Regen Ther
. 2024 Apr;
27:259-267.
PMID: 38601885
Introduction: Vascular tissue engineering is a key technology in the field of regenerative medicine. In tissue engineering, the separation of vascular cells without cell modification is required, as cell modifications...
5.
Nagase K
Anal Sci
. 2024 Apr;
40(5):827-841.
PMID: 38584205
In recent decades, various bioanalytical technologies have been investigated for appropriate medical treatment and effective therapy. Temperature-responsive chromatography is a promising bioanalytical technology owing to its functional properties. Temperature-responsive chromatography...
6.
Nagase K, Nagaoka M, Nakano Y, Utoh R
J Control Release
. 2023 Dec;
366:160-169.
PMID: 38154542
Hepatic tissue engineering has been applied for the treatment of intractable liver diseases, and hepatocyte sheets are promising for this purpose. However, hepatocyte sheets have poor survival after transplantation because...
7.
Nakao M, Matsui M, Kim K, Nishiyama N, Grainger D, Okano T, et al.
Stem Cell Res Ther
. 2023 Dec;
14(1):352.
PMID: 38072920
Background: Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have recently attracted attention as an alternative approach to injected cell suspensions for stem cell therapy. However, cell engraftment and cytokine...
8.
Nagase K, Wakayama H, Matsuda J, Kojima N, Kanazawa H
Mater Today Bio
. 2023 May;
20:100627.
PMID: 37122838
During the last few decades, thermoresponsive materials for modulating cell adhesion have been investigated for the application of tissue engineering. In this study, we developed thermoresponsive mixed polymer brushes consisting...
9.
Nagase K, Yamazaki K, Maekawa Y, Kanazawa H
Mater Today Bio
. 2023 Jan;
18:100521.
PMID: 36590982
The existing methods for exosome isolation, such as ultracentrifugation, size exclusion, and affinity separation, suffer from some limitations. Herein, we aimed to develop temperature-modulated exosome-capturing materials using thermoresponsive polymers and...
10.
Takahashi H, Wakayama H, Nagase K, Shimizu T
Small Methods
. 2022 Dec;
7(2):e2200849.
PMID: 36562139
In preclinical drug testing, human muscle tissue models are critical to understanding the complex physiology, including drug effects in the human body. This study reports that a multilayering approach to...