Kenichi Nagase
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Explore the profile of Kenichi Nagase including associated specialties, affiliations and a list of published articles.
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81
Citations
810
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Recent Articles
11.
Nagase K, Okada A, Matsuda J, Ichikawa D, Hattori Y, Kanazawa H
Colloids Surf B Biointerfaces
. 2022 Oct;
220:112928.
PMID: 36257279
Adipose-derived mesenchymal stem cells (ADSCs) have beneficial effects in cell transplantation therapy; these cells are collected from adipose tissue using low-invasive methods. However, to prepare ADSCs for cell therapy, a...
12.
Nagase K, Kojima N, Goto M, Akaike T, Kanazawa H
J Mater Chem B
. 2022 Aug;
10(42):8629-8641.
PMID: 35972447
Hepatic tissue engineering may be an effective approach for the treatment of liver disease; however, its practical application requires hepatic cell separation technologies that do not involve cell surface modification...
13.
Nagase K, Takagi H, Nakada H, Ishikawa H, Nagata Y, Aomori T, et al.
Sci Rep
. 2022 Jul;
12(1):12847.
PMID: 35896711
Therapeutic drug monitoring, which is used to determine appropriate drug doses, is critical in pharmacological therapy. In this study, we developed thermoresponsive chromatography columns with various cationic properties for effective...
14.
Nagase K, Matsumoto K, Kanazawa H
Sci Rep
. 2022 Mar;
12(1):4434.
PMID: 35292748
In this study, mixed-mode chromatography columns have been investigated using multiple analyte interactions. A mixed-mode chromatography column was developed using poly(N-isopropylacrylamide) (PNIPAAm) brush-modified silica beads and poly(3-acrylamidopropyl trimethylammonium chloride) (PAPTAC)...
15.
Nagase K, Inoue S, Inoue M, Kanazawa H
Sci Rep
. 2022 Feb;
12(1):2653.
PMID: 35173260
Therapeutic drug monitoring (TDM) is an effective pharmacological approach for controlling drug concentration in a patient's serum. Herein, a new two-dimensional chromatography system was developed using two poly(N-isopropylacrylamide) (PNIPAAm)-modified bead-packed...
16.
Nagase K, Nishiyama T, Inoue M, Kanazawa H
Sci Rep
. 2021 Dec;
11(1):23508.
PMID: 34873248
Therapeutic drug monitoring is a key technology for effective pharmacological treatment. In the present study, a temperature-responsive chromatography column was developed for safe and simple therapeutic drug monitoring without the...
17.
Nagase K, Ishizawa Y, Inoue M, Kokubun M, Yamada S, Kanazawa H
Anal Chim Acta
. 2021 Sep;
1179:338806.
PMID: 34535268
We present a temperature-responsive spin column using an all-aqueous eluent. The method is intended as a simple sample preparation method for protein removal from serum, which is required for serum...
18.
Nagase K
Adv Colloid Interface Sci
. 2021 Jul;
295:102487.
PMID: 34314989
Poly(N-isopropylacrylamide) (PNIPAAm) is the most well-known and widely used stimuli-responsive polymer in the biomedical field owing to its ability to undergo temperature-dependent hydration and dehydration with temperature variations, causing hydrophilic...
19.
Nagase K, Edatsune G, Nagata Y, Matsuda J, Ichikawa D, Yamada S, et al.
Biomater Sci
. 2021 Jul;
9(21):7054-7064.
PMID: 34296234
Cell therapy using mesenchymal stem cells (MSCs) is used as effective regenerative treatment. Cell therapy requires effective cell separation without cell modification and cellular activity reduction. In this study, we...
20.
Nomoto D, Nagase K, Nakamura Y, Kanazawa H, Citterio D, Hiruta Y
Colloids Surf B Biointerfaces
. 2021 Jun;
205:111890.
PMID: 34089966
Although the field of antibody drugs has grown larger, the antibody production still faces several challenges. Effective antibody purification is required, but the conventional purification method for antibodies is cost...