Ken Berglund
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Explore the profile of Ken Berglund including associated specialties, affiliations and a list of published articles.
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45
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1036
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Recent Articles
1.
Skelton H, Grogan D, Kotlure A, Berglund K, Gutekunst C, Gross R
J Neurosci Methods
. 2024 Nov;
414:110314.
PMID: 39532188
Background: Physical exercise has been extensively studied for its therapeutic properties in neurological disease, particularly Parkinson's Disease (PD). However, the established techniques for exercise in mice are not well suited...
2.
Stern M, Cole E, Gutekunst C, Yang J, Berglund K, Gross R
bioRxiv
. 2024 Oct;
PMID: 39386598
During cortical spreading depolarization (CSD), neurons exhibit a dramatic increase in cytosolic calcium, which may be integral to CSD-mediated seizure termination. This calcium increase greatly exceeds that during seizures, suggesting...
3.
Stern M, Dingledine R, Gross R, Berglund K
Front Neurol
. 2024 Sep;
15:1465232.
PMID: 39268067
Despite an abundance of pharmacologic and surgical epilepsy treatments, there remain millions of patients suffering from poorly controlled seizures. One approach to closing this treatment gap may be found through...
4.
Merolla A, Michetti C, Moschetta M, Vacca F, Ciano L, Emionite L, et al.
Nat Commun
. 2024 Jul;
15(1):5609.
PMID: 38965228
Epilepsy affects 1% of the general population and 30% of patients are resistant to antiepileptic drugs. Although optogenetics is an efficient antiepileptic strategy, the difficulty of illuminating deep brain areas...
5.
Jiang M, Yu S, Estaba T, Choi E, Berglund K, Gu X, et al.
Cells
. 2024 Jun;
13(11.
PMID: 38891029
Glioblastoma Multiforme (GBM) is an aggressive brain tumor with a high mortality rate. Direct reprogramming of glial cells to different cell lineages, such as induced neural stem cells (iNSCs) and...
6.
Stern M, Cole E, Gross R, Berglund K
Neurophotonics
. 2024 Jan;
11(2):024202.
PMID: 38274784
Significance: Intravital cellular calcium imaging has emerged as a powerful tool to investigate how different types of neurons interact at the microcircuit level to produce seizure activity, with newfound potential...
7.
Stern M, Cole E, Gross R, Berglund K
bioRxiv
. 2023 Oct;
PMID: 37808822
Significance: Genetic cellular calcium imaging has emerged as a powerful tool to investigate how different types of neurons interact at the microcircuit level to produce seizure activity, with newfound potential...
8.
Shim S, Berglund K, Yu S
Neurodegener Dis
. 2023 Sep;
23(1-2):1-12.
PMID: 37666228
Background: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on...
9.
Yu S, Jiang M, Berglund K, Wei L
Alzheimers Dement
. 2023 Jul;
19(9):4267-4269.
PMID: 37485581
Our recent investigation revealed that deficiency of N-methyl-D-aspartate (NMDA) receptor subunit GluN3A (NR3A) is a trigger for chronic neuronal hyperactivity and disruptionFfepspof Ca homeostasis, leading to sporadic Alzheimer's disease (AD)...
10.
Ecanow A, Berglund K, Carrasco D, Isaacson R, English A
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555724
Introduction-Recovery from peripheral nerve injuries is poor even though injured peripheral axons can regenerate. Novel therapeutic approaches are needed. The most successful preclinical experimental treatments have relied on increasing the...