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Guoping Feng

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Articles 211
Citations 15382
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Recent Articles
1.
Mei Y, Gosztyla M, Tan X, Dozier L, Wilkinson B, McKetney J, et al.
Cell Syst . 2025 Mar; :101204. PMID: 40054464
The molecular composition of the excitatory synapse is incompletely defined due to its dynamic nature across developmental stages and neuronal populations. To address this gap, we apply proteomic mass spectrometry...
2.
Dragoi T, Sugihara H, Le N, Adam E, Sharma J, Feng G, et al.
Curr Biol . 2025 Feb; 35(5):1095-1106.e7. PMID: 39970916
Marmosets are emerging rapidly as experimental models for studying the neural bases of cognition and, importantly, for modeling disorders of human cognition, but many aspects of their mental attributes remain...
3.
Yun D, Park Y, Cho J, Kamentsky L, Evans N, DiNapoli N, et al.
Nat Biotechnol . 2025 Jan; PMID: 39856430
Extending single-cell analysis to intact tissues while maintaining organ-scale spatial information poses a major challenge due to unequal chemical processing of densely packed cells. Here we introduce Continuous Redispersion of...
4.
Hartley N, Krol A, Choi S, Rome N, Levandowski K, Pasqualoni S, et al.
Cell Rep . 2024 Dec; 43(12):115037. PMID: 39630580
The thalamic reticular nucleus (TRN), the major inhibitory source of the thalamus, plays essential roles in sensory processing, attention, and cognition. However, our understanding of how TRN circuitry contributes to...
5.
Kang J, Schroeder M, Lee Y, Kapoor C, Yu E, Tarr T, et al.
Nat Commun . 2024 Nov; 15(1):9722. PMID: 39521775
Proteins work together in nanostructures in many physiological contexts and disease states. We recently developed expansion revealing (ExR), which expands proteins away from each other, in order to support better...
6.
Schroeder M, McCormack D, Metzner L, Kang J, Li K, Yu E, et al.
bioRxiv . 2024 Oct; PMID: 39416060
Astrocytes are an abundant class of glial cells with critical roles in neural circuit assembly and function. Though many studies have uncovered significant molecular distinctions between astrocytes from different brain...
7.
Megagiannis P, Mei Y, Yan R, Yuan L, Wilde J, Eckersberg H, et al.
Cell Rep . 2024 Aug; 43(8):114637. PMID: 39154337
Reactive changes of glial cells during neuroinflammation impact brain disorders and disease progression. Elucidating the mechanisms that control reactive gliosis may help us to understand brain pathophysiology and improve outcomes....
8.
Kaiser T, Dattero J, Li L, Chen M, Jiang M, Harrahill A, et al.
eNeuro . 2024 Jun; 11(7). PMID: 38926085
Microglia carry out important functions as the resident macrophages of the brain. To study their role in health and disease, the research community needs tools to genetically modify them with...
9.
Park J, Wang J, Guan W, Gjesteby L, Pollack D, Kamentsky L, et al.
Science . 2024 Jun; 384(6701):eadh9979. PMID: 38870291
Understanding cellular architectures and their connectivity is essential for interrogating system function and dysfunction. However, we lack technologies for mapping the multiscale details of individual cells and their connectivity in...
10.
Chung M, Imanaka K, Huang Z, Watarai A, Wang M, Tao K, et al.
Nat Commun . 2024 Jun; 15(1):4531. PMID: 38866749
Individuals with autism spectrum disorder (ASD) have a higher prevalence of social memory impairment. A series of our previous studies revealed that hippocampal ventral CA1 (vCA1) neurons possess social memory...