Kelvin W Gee
Overview
Explore the profile of Kelvin W Gee including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
306
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Balleste A, Sangadi A, Titus D, Johnstone T, Hogenkamp D, Gee K, et al.
Exp Neurol
. 2024 Jun;
379:114879.
PMID: 38942266
Traumatic brain injury (TBI) leads to changes in the neural circuitry of the hippocampus that result in chronic learning and memory deficits. However, effective therapeutic strategies to ameliorate these chronic...
2.
Sangadi D, Sangadi A, Placeres-Uray F, Titus D, Johnstone T, Hogenkamp D, et al.
Exp Neurol
. 2023 Dec;
372:114647.
PMID: 38070724
Traumatic brain injury (TBI) results in several pathological changes within the hippocampus that result in adverse effects on learning and memory. Therapeutic strategies to enhance learning and memory after TBI...
3.
Belelli D, Hogenkamp D, Gee K, Lambert J
Neurobiol Stress
. 2020 May;
12:100207.
PMID: 32435660
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABA receptor (GABAR). These reports were followed...
4.
Titus D, Johnstone T, Johnson N, London S, Chapalamadugu M, Hogenkamp D, et al.
PLoS One
. 2019 Oct;
14(10):e0223180.
PMID: 31581202
Cognitive impairments are a common consequence of traumatic brain injury (TBI). The hippocampus is a subcortical structure that plays a key role in the formation of declarative memories and is...
5.
Johnstone T, McCarren H, Spampanato J, Dudek F, McDonough J, Hogenkamp D, et al.
Front Pharmacol
. 2019 Jun;
10:560.
PMID: 31178732
Seizures induced by organophosphorus nerve agent exposure become refractory to treatment with benzodiazepines because these drugs engage synaptic γ-aminobutyric acid-A receptors (GABARs) that rapidly internalize during (SE). Extrasynaptic GABARs, such...
6.
Johnstone T, Xie J, Qu C, Wasiak D, Hogenkamp D, Porreca F, et al.
Pain
. 2018 Sep;
160(1):198-209.
PMID: 30204648
Chronic neuropathic pain may be caused, in part, by loss of inhibition in spinal pain processing pathways due to attenuation of local GABAergic tone. Nociception and nocifensive behaviors are reduced...
7.
Reddy D, Yoshimura R, Ramanathan G, Carver C, Johnstone T, Hogenkamp D, et al.
Epilepsy Behav
. 2018 Mar;
82:57-63.
PMID: 29587186
Objective: Subunit-specific positive allosteric modulators (PAMs) of gamma-aminobutyric acid-A (GABA-A) receptors are commonly used to uncover the role of GABA-A receptor isoforms in brain function. Recently, we have designed novel...
8.
Yoshimura R, Tran M, Hogenkamp D, Ayala N, Johnstone T, Dunnigan A, et al.
Neuropharmacology
. 2017 Aug;
126:38-47.
PMID: 28842344
Autism spectrum disorder (ASD) is associated with two core symptoms (social communication deficits and stereotyped repetitive behaviors) in addition to a number of comorbidities. There are no FDA-approved drugs for...
9.
Gee K, Olincy A, Kanner R, Johnson L, Hogenkamp D, Harris J, et al.
J Psychopharmacol
. 2017 Feb;
31(4):434-441.
PMID: 28196430
Type I positive allosteric modulators (PAMs) of the alpha7-nicotinic receptor enhance its cholinergic activation while preserving the spatiotemporal features of synaptic transmission and the receptor's characteristic rapid desensitization kinetics. Alpha7-nicotinic...
10.
Hogenkamp D, Tran M, Yoshimura R, Johnstone T, Kanner R, Gee K
Psychopharmacology (Berl)
. 2014 Apr;
231(17):3517-24.
PMID: 24682501
Rationale: In order to improve upon the pharmacological properties of the neuroactive steroid ganaxolone, it was used as the starting point in the design of novel neurosteroids that replace the...