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James D Belluzzi

Explore the profile of James D Belluzzi including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1041
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Recent Articles
1.
Reynaga D, Cano M, Belluzzi J, Leslie F
Adv Drug Alcohol Res . 2024 Feb; 3:11324. PMID: 38389812
The aim of the current study was to determine whether non-nicotine constituents of cigarette smoke contribute to nicotine dependence in adolescent and adult male Sprague Dawley rats. For 10 days...
2.
Gellner C, Carreno D, Belluzzi J, Leslie F
Front Psychiatry . 2023 Feb; 14:1096213. PMID: 36815196
Introduction: Given the rapid increase in teen vaping over recent years it is critical to understand mechanisms underlying addiction and relapse to tobacco use at this age. To evaluate the...
3.
Cano M, Reynaga D, Belluzzi J, Loughlin S, Leslie F
Neuropharmacology . 2020 Sep; 181:108308. PMID: 32950561
Heavy smokers display increased radioligand binding of nicotinic acetylcholine receptors (nAChRs). This "upregulation" is thought to be a contributing factor to tobacco dependence. Although cigarette smoke contains thousands of constituents...
4.
Dwyer J, Cardenas A, Franke R, Chen Y, Bai Y, Belluzzi J, et al.
Transl Psychiatry . 2019 Nov; 9(1):304. PMID: 31740669
Despite persistent public health initiatives, many women continue to smoke during pregnancy. Since maternal smoking has been linked to persisting sex-dependent neurobehavioral deficits in offspring, some consider nicotine to be...
5.
Cross S, Reynaga D, Cano M, Belluzzi J, Zaveri N, Leslie F
Neuropharmacology . 2019 Nov; 162:107846. PMID: 31704271
Despite extensive research, current therapies for smoking cessation are largely ineffective at maintaining abstinence for more than a year. Whereas most preclinical studies use nicotine alone, the goal of the...
6.
Yuan M, Malagon A, Yasuda D, Belluzzi J, Leslie F, Zaveri N
Behav Brain Res . 2017 Jul; 333:251-257. PMID: 28693859
The strong reinforcing effects of nicotine and the negative symptoms such as anxiety experienced during a quit attempt often lead to relapse and low success rates for smoking cessation. Treatments...
7.
Larraga A, Belluzzi J, Leslie F
Front Behav Neurosci . 2017 Mar; 11:25. PMID: 28275339
Use of alcohol and tobacco, the two most concurrently abused drugs, typically first occurs during adolescence. Yet, there have been no systematic analyses of ethanol (EtOH) and nicotine (Nic) interactions...
8.
Gellner C, Belluzzi J, Leslie F
Neuropharmacology . 2016 Jun; 109:247-253. PMID: 27346207
Although smoking initiation typically occurs during adolescence, most preclinical studies of tobacco use involve adult animals. Furthermore, their focus is largely on nicotine alone, even though cigarette smoke contains thousands...
9.
Wang L, Alachkar A, Sanathara N, Belluzzi J, Wang Z, Civelli O
Int J Neuropsychopharmacol . 2015 May; 18(12). PMID: 25991655
Background: Modulating the methylation process induces broad biochemical changes, some of which may be involved in schizophrenia. Methylation is in particular central to epigenesis, which is also recognized as a...
10.
Arnold M, Loughlin S, Belluzzi J, Leslie F
Neuropharmacology . 2014 Jun; 85:293-304. PMID: 24907588
Tobacco use is the leading cause of preventable death. Although the health risks are well known, cessation rates remain low. Whereas behavioral and neuroanatomical studies on tobacco addiction conventionally use...