Kelsey R Bounds
Overview
Explore the profile of Kelsey R Bounds including associated specialties, affiliations and a list of published articles.
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9
Citations
253
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Recent Articles
1.
Chatterjee P, Chiasson V, Kopriva S, Bounds K, Newell-Rogers M, Mitchell B
Pregnancy Hypertens
. 2018 Sep;
13:154-160.
PMID: 30177045
Objective: Innate immune system activation and excessive inflammation contributes to hypertension during pregnancy (HTN-preg). Activation of Toll-like receptors (TLRs), the primary innate immune system sensor, is evident in women with...
2.
Chiasson V, Bounds K, Chatterjee P, Manandhar L, Pakanati A, Hernandez M, et al.
Hypertension
. 2017 Nov;
71(1):199-207.
PMID: 29133357
The calcineurin inhibitor cyclosporine A (CsA) suppresses the immune system but promotes hypertension, vascular dysfunction, and renal damage. CsA decreases regulatory T cells and this contributes to the development of...
3.
Li L, Bounds K, Chatterjee P, Gupta S
J Am Heart Assoc
. 2017 Nov;
6(11).
PMID: 29114000
Background: Cardiac fibrosis occurs because of disruption of the extracellular matrix network leading to myocardial dysfunction. Angiotensin II has been implicated in the development of cardiac fibrosis. Recently, microRNAs have...
4.
Bounds K, Chiasson V, Pan L, Gupta S, Chatterjee P
Front Cardiovasc Med
. 2017 Oct;
4:60.
PMID: 28993808
Our understanding of how microRNAs (miRNAs) regulate gene networks and affect different molecular pathways leading to various human pathologies has significantly improved over the years. In contrary, the role of...
5.
Chatterjee P, Chiasson V, Seerangan G, De Guzman E, Milad M, Bounds K, et al.
Clin Sci (Lond)
. 2017 Jun;
131(15):2047-2058.
PMID: 28642294
Excessive innate immune system activation and inflammation during pregnancy can lead to organ injury and dysfunction and preeclampsia (PE); however, the molecular mechanisms involved are unknown. We tested the hypothesis...
6.
Chiasson V, Pakanati A, Hernandez M, Young K, Bounds K, Mitchell B
Hypertension
. 2017 Jun;
70(1):183-191.
PMID: 28584011
The immunosuppressive calcineurin inhibitors cyclosporine A and tacrolimus alter T-cell subsets and can cause hypertension, vascular dysfunction, and renal toxicity. We and others have reported that cyclosporine A and tacrolimus...
7.
Chatterjee P, Chiasson V, Pinzur L, Raveh S, Abraham E, Jones K, et al.
Clin Sci (Lond)
. 2015 Dec;
130(7):513-23.
PMID: 26685104
Pre-eclampsia, the development of hypertension and proteinuria or end-organ damage during pregnancy, is a leading cause of both maternal and fetal morbidity and mortality, and there are no effective clinical...
8.
Bounds K, Newell-Rogers M, Mitchell B
Front Cardiovasc Med
. 2015 Dec;
2:20.
PMID: 26664892
The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE). We propose four pathways that involve excessive...
9.
Chatterjee P, Chiasson V, Bounds K, Mitchell B
Front Immunol
. 2014 Jun;
5:253.
PMID: 24904596
Inflammation mediated by both innate and adaptive immune cells is necessary for several important processes during pregnancy. Pro-inflammatory immune cell activation plays a critical role in embryo implantation, placentation, and...