Brett M Mitchell
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Explore the profile of Brett M Mitchell including associated specialties, affiliations and a list of published articles.
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64
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1351
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Recent Articles
1.
Smith H, Goodlett B, Navaneethabalakrishnan S, Mitchell B
Cells
. 2024 Aug;
13(15.
PMID: 39120331
Hypertension (HTN) impacts almost half of adults, predisposing them to cardiovascular disease and renal damage. Salt-sensitive HTN (SSHTN) and angiotensin II (A2)-induced HTN (A2HTN) both involve immune system activation and...
2.
McDermott J, Goodlett B, Creed H, Navaneethabalakrishnan S, Rutkowski J, Mitchell B
Kidney Blood Press Res
. 2024 Jul;
49(1):588-604.
PMID: 38972305
Introduction: Hypertension (HTN) is a major cardiovascular disease that can cause and be worsened by renal damage and inflammation. We previously reported that renal lymphatic endothelial cells (LECs) increase in...
3.
Navaneethabalakrishnan S, Goodlett B, Smith H, Montalvo 2nd R, Cardenas A, Mitchell B
Clin Sci (Lond)
. 2024 Jul;
138(14):921-940.
PMID: 38949840
Salt-sensitive hypertension (SSHTN) is associated with M1 macrophage polarization and inflammatory responses, leading to inflammation-associated lymphangiogenesis and functional impairment across multiple organs, including kidneys and gonads. However, it remains unclear...
4.
Navaneethabalakrishnan S, Goodlett B, Smith H, Cardenas A, Burns A, Mitchell B
Clin Sci (Lond)
. 2024 Jul;
138(14):901-920.
PMID: 38949825
We reported that salt-sensitive hypertension (SSHTN) is associated with increased pro-inflammatory immune cells, inflammation, and inflammation-associated lymphangiogenesis in the kidneys and gonads of male and female mice. However, it is...
5.
Creed H, Kannan S, Tate B, Godefroy D, Banerjee P, Mitchell B, et al.
J Am Soc Nephrol
. 2024 Mar;
35(5):549-565.
PMID: 38506705
Significance Statement: The renal lymphatic vasculature and the lymphatic endothelial cells that make up this network play important immunomodulatory roles during inflammation. How lymphatics respond to AKI may affect AKI...
6.
Rossitto G, Bertoldi G, Rutkowski J, Mitchell B, Delles C
Hypertension
. 2024 Feb;
81(4):727-737.
PMID: 38385255
Blood pressure is regulated by vascular resistance and intravascular volume. However, exchanges of electrolytes and water between intra and extracellular spaces and filtration of fluid and solutes in the capillary...
7.
Creed H, Kannan S, Tate B, Banerjee P, Mitchell B, Chakraborty S, et al.
bioRxiv
. 2023 Jun;
PMID: 37333313
The inflammatory response to acute kidney injury (AKI) likely dictates future renal health. Lymphatic vessels are responsible for maintaining tissue homeostasis through transport and immunomodulatory roles. Due to the relative...
8.
Baranwal G, Goodlett B, Arenaz C, Creed H, Navaneethabalakrishnan S, Rutkowski J, et al.
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298145
Hypertension affects over a billion adults worldwide and is a major risk factor for cardiovascular disease. Studies have reported that the microbiota and its metabolites regulate hypertension pathophysiology. Recently, tryptophan...
9.
Goodlett B, Balasubbramanian D, Navaneethabalakrishnan S, Love S, Luera E, Konatham S, et al.
Clin Sci (Lond)
. 2022 Nov;
136(23):1759-1772.
PMID: 36345993
Background: Hypertension (HTN) is associated with renal proinflammatory immune cell infiltration and increased sodium retention. We reported previously that renal lymphatic vessels, which are responsible for trafficking immune cells from...
10.
Wilcox B, Henley M, Navaneethabalakrishnan S, Martinez K, Pournouri A, Goodlett B, et al.
Cells
. 2022 Jul;
11(14).
PMID: 35883582
(1) Background: Renal immune cells and lymphatic vessel (LV) density have been reported previously to be increased in multiple mouse models of hypertension (HTN). However, whether interstitial levels of HTN...