Kelly E Corcoran
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Explore the profile of Kelly E Corcoran including associated specialties, affiliations and a list of published articles.
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12
Citations
351
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Recent Articles
1.
Patel S, Meyer J, Greco S, Corcoran K, Bryan M, Rameshwar P
J Immunol
. 2010 Apr;
184(10):5885-94.
PMID: 20382885
Mesenchymal stem cells (MSCs) have been shown to support breast cancer growth. Because MSCs also increase the frequency of regulatory T cells (T(regs)), this study tested the hypothesis that human...
2.
Corcoran K, Trzaska K, Fernandes H, Bryan M, Taborga M, Srinivas V, et al.
PLoS One
. 2008 Jun;
3(6):e2563.
PMID: 18575622
Background: An understanding of BC cell (BCC) entry into bone marrow (BM) at low tumor burden is limited when compared to highly metastatic events during heavy tumor burden. BCCs can...
3.
Corcoran K, Malhotra A, Molina C, Rameshwar P
J Mol Endocrinol
. 2008 Mar;
40(3):113-23.
PMID: 18316470
The chemokine Stromal-derived factor-1alpha (SDF-1alpha) interacts with seven transmembrane (TM) G-protein-coupled receptor (GPR), CXCR4. SDF-1alpha is linked to inflammation, chemoattraction, cancer metastasis, and hematopoiesis. Tachykinin (Tac1) peptides bind seven transmembrane...
4.
Corcoran K, Rameshwar P
Mol Cancer Res
. 2007 Apr;
5(4):373-81.
PMID: 17409218
Stromal cell-derived factor-1alpha (SDF-1alpha) is a CXC chemokine that interacts with CXCR4 receptor. Tac1 encodes peptides belonging to the tachykinins, including substance P. SDF-1alpha production is decreased in Tac1 knockdown...
5.
Taborga M, Corcoran K, Fernandes N, Ramkissoon S, Rameshwar P
Mini Rev Med Chem
. 2007 Mar;
7(3):245-51.
PMID: 17346217
Breast cancer remains a leading cause of death despite early screening and advances in medicine. Bone marrow metastasis often complicates the clinical picture by requiring more aggressive treatment and worsening...
6.
Corcoran K, Patel N, Rameshwar P
J Immunol
. 2007 Feb;
178(4):2075-82.
PMID: 17277111
Stromal cell-derived growth factor-1alpha (SDF-1alpha) is a member of the CXC chemokines and interacts with the G protein, seven-transmembrane CXCR4 receptor. SDF-1alpha acts as a chemoattractant for immune and hemopoietic...
7.
Singh A, Caplan A, Corcoran K, Fernandez J, Preziosi M, Rameshwar P
Vascul Pharmacol
. 2006 Aug;
45(4):235-42.
PMID: 16901764
Breast cancer (BC) remains the cancer with highest mortality among women in the United States. Entry of BC cells (BCCs) in bone marrow (BM) leads to poor prognosis. This review...
8.
Moharita A, Taborga M, Corcoran K, Bryan M, Patel P, Rameshwar P
Blood
. 2006 Jul;
108(10):3245-52.
PMID: 16857992
Breast cancer cells (BCCs) show preference for the bone marrow (BM). An animal model showed 2 populations of BCCs in the BM with regard to their cycling states. An in...
9.
Harrison J, Corcoran K, Joshi D, Sophacleus C, Rameshwar P
Am J Hematol
. 2005 Dec;
81(1):51-8.
PMID: 16369977
Myelofibrosis is an uncommon phenomenon associated with a variety of neoplastic and inflammatory processes. Although there is evidence that cytokines elaborated by clonal malignant hematopoietic cells are implicated in myelofibrosis...
10.
Claps C, Corcoran K, Cho K, Rameshwar P
Curr Neurovasc Res
. 2005 Sep;
2(4):319-29.
PMID: 16181123
This review extrapolates the functions of SDF-1alpha and its receptor, CXCR4, as regulators of hematopoietic stem cells and discusses their potential roles in the development and regeneration of tissues. The...