Kellie Vinal
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Explore the profile of Kellie Vinal including associated specialties, affiliations and a list of published articles.
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4
Citations
73
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Recent Articles
1.
Vinal K, Conn G
Antimicrob Agents Chemother
. 2017 Mar;
61(5).
PMID: 28289026
The pathogen-associated 16S rRNA methyltransferase NpmA catalyzes mA1408 modification to block the action of structurally diverse aminoglycoside antibiotics. Here, we describe the development of a fluorescence polarization binding assay and...
2.
Savic M, Sunita S, Zelinskaya N, Desai P, Macmaster R, Vinal K, et al.
Antimicrob Agents Chemother
. 2015 Mar;
59(5):2807-16.
PMID: 25733511
Methylation of bacterial 16S rRNA within the ribosomal decoding center confers exceptionally high resistance to aminoglycoside antibiotics. This resistance mechanism is exploited by aminoglycoside producers for self-protection while functionally equivalent...
3.
Dunkle J, Vinal K, Desai P, Zelinskaya N, Savic M, West D, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(17):6275-80.
PMID: 24717845
Aminoglycosides are potent, broad spectrum, ribosome-targeting antibacterials whose clinical efficacy is seriously threatened by multiple resistance mechanisms. Here, we report the structural basis for 30S recognition by the novel plasmid-mediated...
4.
Sueyoshi T, Green W, Vinal K, Woodrum T, Moore R, Negishi M
PLoS One
. 2011 Jun;
6(6):e21229.
PMID: 21698271
Constituent chemicals in garlic extract are known to induce phase I and phase II enzymes in rodent livers. Here we have utilized Car(+/+) and Car(-/-) mice to demonstrate that the...