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Keld Kaltoft

Explore the profile of Keld Kaltoft including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 185
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Recent Articles
1.
Kollgaard T, Duval L, Schmidt H, Kaltoft K, Seremet T, Andersen M, et al.
Cytotherapy . 2009 Jun; 11(5):631-41. PMID: 19530030
Background Aims: Adoptive transfer of tumor-specific lymphocytes is a promising strategy in the treatment of cancer. We conducted intratumoral administration of an allogeneic irradiated continuous T-cell line (C-Cure 709) expressing...
2.
Corydon T, Haagerup A, Jensen T, Binderup H, Petersen M, Kaltoft K, et al.
J Med Genet . 2007 May; 44(8):509-15. PMID: 17513529
Background: Several studies have documented a substantial genetic component in the aetiology of allergic diseases and a number of atopy susceptibility loci have been suggested. One of these loci is...
3.
Duval L, Schmidt H, Kaltoft K, Fode K, Jensen J, Sorensen S, et al.
Clin Cancer Res . 2006 Feb; 12(4):1229-36. PMID: 16489078
Purpose: We did a phase I dose-escalation trial to evaluate the feasibility and safety of intratumoral injections of C Cure 709, an allogeneic, continuous CTL cell line that, restricted by...
4.
Eriksen K, Lovato P, Skov L, Krejsgaard T, Kaltoft K, Geisler C, et al.
J Invest Dermatol . 2005 Nov; 125(5):936-44. PMID: 16297193
Psoriasis is a chronic inflammatory skin disease characterized by abnormal epidermal proliferation. Several studies have shown that skin-infiltrating activated T cells and cytokines play a pivotal role during the initiation...
5.
Agnholt J, Dahlerup J, Kaltoft K
Cytokine . 2003 Aug; 23(3):76-85. PMID: 12906870
Background/aims: Infliximab (Ifx) is effective in the treatment of Crohn's disease (CD) and rheumatoid arthritis (RA), etanercept (Eta) in RA but not in CD. The mechanisms underlying these clinical differences...
6.
Agnholt J, Kaltoft K, Jakobsen N, Dahlerup J
Cytokines Cell Mol Ther . 2003 Jul; 7(3):117-23. PMID: 12850811
In Crohn's disease (CD) CD4(+) T-cells producing tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) are important for disease progression. T-cell vaccination with such attenuated (gamma-irradiated) CD4(+) T cells may ameliorate...
7.
Lovato P, Brender C, Agnholt J, Kelsen J, Kaltoft K, Svejgaard A, et al.
J Biol Chem . 2003 Mar; 278(19):16777-81. PMID: 12615922
Via cytoplasmic signal transduction pathways, cytokines induce a variety of biological responses and modulate the outcome of inflammatory diseases and malignancies. Crohn's disease is a chronic inflammatory bowel disease of...
8.
Lundin Brockdorff J, Woetmann A, Mustelin T, Kaltoft K, Zhang Q, Wasik M, et al.
Cytokine . 2003 Jan; 20(4):141-7. PMID: 12543077
The phosphotyrosine phosphatase SHP2 has been suggested to regulate activation of MAPK, Stat3, and Stat5 in several experimental models. In this study we investigated the role of SHP2 in IL-2...
9.
Nielsen M, Nissen M, Gerwien J, Zocca M, Rasmussen H, Nakajima K, et al.
Blood . 2002 Jan; 99(3):973-7. PMID: 11807001
Mycosis fungoides is a low-grade cutaneous T-cell lymphoma (CTCL) of unknown etiology. In advanced stages of CTCL, a shift in cytokine profile from T(H)1 to T(H)2 is observed, which coincides...