Keith K Khoo
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Explore the profile of Keith K Khoo including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
280
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Recent Articles
1.
Sarkar D, Galleano I, Heusser S, Ou S, Uzun G, Khoo K, et al.
Cell Chem Biol
. 2023 Dec;
31(5):1000-1010.e6.
PMID: 38113885
Acid-sensing ion channels (ASICs) are trimeric ion channels that open a cation-conducting pore in response to proton binding. Excessive ASIC activation during prolonged acidosis in conditions such as inflammation and...
2.
Elsayed H, Nabi G, McKinstry W, Khoo K, Mak J, Salazar A, et al.
J Virol
. 2022 Feb;
96(3):e0195421.
PMID: 35138145
No abstract available.
3.
Dubois N, Khoo K, Ghossein S, Seissler T, Wolff P, McKinstry W, et al.
RNA Biol
. 2018 Jun;
15(7):923-936.
PMID: 29954247
The Pr55 precursor specifically selects the HIV-1 genomic RNA (gRNA) from a large excess of cellular and partially or fully spliced viral RNAs and drives the virus assembly at the...
4.
Elsayed H, Nabi G, McKinstry W, Khoo K, Mak J, Salazar A, et al.
J Virol
. 2018 May;
92(14).
PMID: 29743369
Induction of persistent antibody responses by vaccination is generally thought to depend on efficient help by T follicular helper cells. Since the T helper cell response to HIV Env may...
5.
6.
Tanwar H, Khoo K, Garvey M, Waddington L, Leis A, Hijnen M, et al.
PLoS Pathog
. 2017 Feb;
13(2):e1006221.
PMID: 28222188
The interactions that occur during HIV Pr55Gag oligomerization and genomic RNA packaging are essential elements that facilitate HIV assembly. However, mechanistic details of these interactions are not clearly defined. Here,...
7.
Schneider E, Huang J, Carbone V, Han M, Zhu Y, Nang S, et al.
ACS Infect Dis
. 2017 Feb;
3(3):249-258.
PMID: 28142234
Daptomycin is a lipopeptide antibiotic that is highly bound to plasma proteins. To date, the plasma components and structure-activity relationships responsible for the plasma protein binding profile of daptomycin remain...
8.
Rashid M, Huq R, Tanner M, Chhabra S, Khoo K, Estrada R, et al.
Sci Rep
. 2014 Mar;
4:4509.
PMID: 24676092
HsTX1 toxin, from the scorpion Heterometrus spinnifer, is a 34-residue, C-terminally amidated peptide cross-linked by four disulfide bridges. Here we describe new HsTX1 analogues with an Ala, Phe, Val or...
9.
Khoo K, Gupta K, Green B, Zhang M, Watkins M, Olivera B, et al.
Biochemistry
. 2012 Nov;
51(49):9826-35.
PMID: 23167564
In the preparation of synthetic conotoxins containing multiple disulfide bonds, oxidative folding can produce numerous permutations of disulfide bond connectivities. Establishing the native disulfide connectivities thus presents a significant challenge...
10.
Ye M, Khoo K, Xu S, Zhou M, Boonyalai N, Perugini M, et al.
J Biol Chem
. 2012 Mar;
287(18):14973-83.
PMID: 22399292
Cone snail venoms are a rich source of peptides, many of which are potent and selective modulators of ion channels and receptors. Here we report the isolation and characterization of...