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Keith Gagnon

Explore the profile of Keith Gagnon including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Nukala S, Jousma J, Yan G, Han Z, Kwon Y, Cho Y, et al.
Cardiovasc Res . 2023 Jun; 119(10):1997-2013. PMID: 37267414
Aims: Novel cancer therapies leading to increased survivorship of cancer patients have been negated by a concomitant rise in cancer therapies-related cardiovascular toxicities. Sunitinib, a first line multi-receptor tyrosine kinase...
2.
Biswas S, Buhrman G, Gagnon K, Mattos C, Brown 2nd B, Maxwell E
Biochemistry . 2011 Mar; 50(14):2907-18. PMID: 21366326
Box C/D ribonucleoproteins (RNP) guide the 2'-O-methylation of targeted nucleotides in archaeal and eukaryotic rRNAs. The archaeal L7Ae and eukaryotic 15.5kD box C/D RNP core protein homologues initiate RNP assembly...
3.
Gagnon K, Zhang X, Maxwell E
Methods Enzymol . 2007 Aug; 425:263-82. PMID: 17673088
Archaeal box C/D RNAs guide the site-specific 2'-O-methylation of target nucleotides in ribosomal RNAs and tRNAs. In vitro reconstitution of catalytically active box C/D RNPs by use of in vitro...