Keith B Elkon
Overview
Explore the profile of Keith B Elkon including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
84
Citations
4325
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
12.
Akilesh H, Buechler M, Duggan J, Hahn W, Matta B, Sun X, et al.
Science
. 2019 Jan;
363(6423).
PMID: 30630901
Cytopenias are an important clinical problem associated with inflammatory disease and infection. We show that specialized phagocytes that internalize red blood cells develop in Toll-like receptor 7 (TLR7)-driven inflammation. TLR7...
13.
An J, Woodward J, Lai W, Minie M, Sun X, Tanaka L, et al.
Arthritis Rheumatol
. 2018 May;
70(11):1807-1819.
PMID: 29781188
Objective: Type I interferon (IFN) is strongly implicated in the pathogenesis of systemic lupus erythematosus (SLE) as well as rare monogenic interferonopathies such as Aicardi-Goutières syndrome (AGS), a disease attributed...
14.
Elkon K
Arthritis Rheumatol
. 2018 Feb;
70(6):805-816.
PMID: 29439290
Cells of the innate immune system are rigged with sensors that detect nucleic acids derived from microbes, especially viruses. It has become clear that these same sensors that respond to...
15.
Lood C, Arve S, Ledbetter J, Elkon K
J Exp Med
. 2017 Jun;
214(7):2103-2119.
PMID: 28606989
Neutrophils play a crucial role in host defense. However, neutrophil activation is also linked to autoimmune diseases such as systemic lupus erythematosus (SLE), where nucleic acid-containing immune complexes (IC) drive...
16.
An J, Durcan L, Karr R, Briggs T, Rice G, Teal T, et al.
Arthritis Rheumatol
. 2016 Nov;
69(4):800-807.
PMID: 27863149
Objective: Type I interferon (IFN) is implicated in the pathogenesis of systemic lupus erythematosus (SLE) and interferonopathies such as Aicardi-Goutières syndrome. A recently discovered DNA-activated type I IFN pathway, cyclic...
17.
Sontheimer C, Liggitt D, Elkon K
Arthritis Rheumatol
. 2016 Nov;
69(4):826-836.
PMID: 27863141
Objective: Photosensitivity is common in patients with systemic lupus erythematosus, although the mechanisms linking ultraviolet (UV) light to flares are not well understood. We undertook this study to determine whether...
18.
Gazitt T, Lood C, Elkon K
Rambam Maimonides Med J
. 2016 Nov;
7(4).
PMID: 27824546
Anti-citrullinated protein antibodies (ACPAs) are highly specific serologic markers for rheumatoid arthritis (RA) and can pre-date clinical disease onset by up to 10 years, also predicting erosive disease. The process...
19.
An J, Minie M, Sasaki T, Woodward J, Elkon K
Annu Rev Med
. 2016 Nov;
68:317-330.
PMID: 27813878
The best known of the naturally occurring antimalarial compounds are quinine, extracted from cinchona bark, and artemisinin (qinghao), extracted from Artemisia annua in China. These and other derivatives are now...
20.
Doedens J, Jones W, Hill K, Mason M, Gersuk V, Mease P, et al.
J Immunol
. 2016 Aug;
197(7):2854-63.
PMID: 27534558
The loss of tolerance and the presence of circulating autoantibodies directed against nuclear Ags is the hallmark of systemic lupus erythematosus (SLE). Many of these Ags are complexed with short,...