Keith A Houck
Overview
Explore the profile of Keith A Houck including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
76
Citations
3440
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Cattley R, Kromhout H, Sun M, Tokar E, Abdallah M, Bauer A, et al.
Lancet Oncol
. 2023 Mar;
24(5):431-432.
PMID: 36966774
No abstract available.
2.
Villeneuve D, Blackwell B, Cavallin J, Collins J, Hoang J, Hofer R, et al.
Environ Sci Technol
. 2023 Feb;
57(9):3794-3803.
PMID: 36800546
Given concerns about potential toxicological hazards of the thousands of data-poor per- and polyfluorinated alkyl substances (PFAS) currently in commerce and detected in the environment, tiered testing strategies that employ...
3.
Houck K, Paul Friedman K, Feshuk M, Patlewicz G, Smeltz M, Clifton M, et al.
ALTEX
. 2022 Sep;
40(2):248–270.
PMID: 36129398
A structurally diverse set of 147 per- and polyfluoroalkyl substances (PFAS) was screened in a panel of 12 human primary cell systems by measuring 148 biomarkers relevant to (patho)physiological pathways...
4.
Medvedev A, Moeser M, Medvedeva L, Martsen E, Granick A, Raines L, et al.
Sci Rep
. 2022 Feb;
12(1):3115.
PMID: 35210493
Nuclear receptors (NR) are ligand-modulated transcription factors that regulate multiple cell functions and thus represent excellent drug targets. However, due to a considerable NR structural homology, NR ligands often interact...
5.
Korunes K, Liu J, Huang R, Xia M, Houck K, Corton J
PLoS One
. 2022 Feb;
17(2):e0261854.
PMID: 35108274
The nuclear factor-kappa B (NF-κB) is a transcription factor with important roles in inflammation, immune response, and oncogenesis. Dysregulation of NF-κB signaling is associated with inflammation and certain cancers. We...
6.
Han J, Gu W, Barrett H, Yang D, Tang S, Sun J, et al.
Environ Health Perspect
. 2021 Jul;
129(7):77004.
PMID: 34288731
Background: Thousands of per- and polyfluoroalkyl substances (PFAS) with diverse structures have been detected in the ambient environment. Apart from a few well-studied PFAS, the structure-related toxicokinetics of a broader...
7.
Park Y, Jung D, Milcamps A, Takeyoshi M, Jacobs M, Houck K, et al.
Food Chem Toxicol
. 2021 Apr;
152:112206.
PMID: 33887398
We describe the characterisation and validation of an androgen receptor (AR) transactivation assay for detection of AR agonists and antagonists using a stably transfected human prostate cancer cell line. This...
8.
Houck K, Patlewicz G, Richard A, Williams A, Shobair M, Smeltz M, et al.
Toxicology
. 2021 Apr;
457:152789.
PMID: 33887376
Per- and polyfluoroalkyl substances (PFAS) are a broad class of hundreds of fluorinated chemicals with environmental health concerns due to their widespread presence and persistence in the environment. Several of...
9.
Franzosa J, Bonzo J, Jack J, Baker N, Kothiya P, Witek R, et al.
NPJ Syst Biol Appl
. 2021 Jan;
7(1):7.
PMID: 33504769
The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and commerce. However, most...
10.
Richard A, Huang R, Waidyanatha S, Shinn P, Collins B, Thillainadarajah I, et al.
Chem Res Toxicol
. 2020 Nov;
34(2):189-216.
PMID: 33140634
Since 2009, the Tox21 project has screened ∼8500 chemicals in more than 70 high-throughput assays, generating upward of 100 million data points, with all data publicly available through partner websites...