Keiichi Higuchi
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Explore the profile of Keiichi Higuchi including associated specialties, affiliations and a list of published articles.
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102
Citations
949
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Recent Articles
1.
Iwaide S, Murakami T, Sedghi Masoud N, Kobayashi N, Fortin J, Miyahara H, et al.
Vet Pathol
. 2024 Oct;
62(2):117-138.
PMID: 39389927
Amyloidosis is a group of diseases in which proteins become amyloid, an insoluble fibrillar aggregate, resulting in organ dysfunction. Amyloid deposition has been reported in various animal species. To diagnose...
2.
Andreotti G, Baur J, Ugrina M, Pfeiffer P, Hartmann M, Wiese S, et al.
J Mol Biol
. 2024 Jan;
436(4):168441.
PMID: 38199491
Amyloid resistance is the inability or the reduced susceptibility of an organism to develop amyloidosis. In this study we have analysed the molecular basis of the resistance to systemic AApoAII...
3.
Motomura E, Inui K, Nakayama Y, Higuchi K, Nakano T, Okubo R, et al.
Neurophysiol Clin
. 2023 Jun;
53(1):102885.
PMID: 37285727
No abstract available.
4.
Kang X, Shimada S, Miyahara H, Higuchi K, Mori M
Mol Genet Metab Rep
. 2023 Mar;
35:100964.
PMID: 36967721
In humans, mutations in the coproporphyrinogen oxidase () gene can result in hereditary coproporphyria (HCP), characterized by high levels of coproporphyrin excretion in the urine and feces, as well as...
5.
Li Y, Dai J, Kametani F, Yazaki M, Ishigami A, Mori M, et al.
Am J Pathol
. 2023 Mar;
193(6):725-739.
PMID: 36965775
Spontaneous and age-related amyloidosis has been reported in C57BL/6J mice. However, the biochemical characteristics of age-related amyloidosis remain unclear. Herein, the age-related prevalence of amyloidosis, the types of amyloid fibril...
6.
Miyahara H, Dai J, Li Y, Cui X, Takeuchi H, Hachiya N, et al.
Amyloid
. 2022 Dec;
30(2):225-238.
PMID: 36495239
Amyloidosis refers to a group of degenerative diseases that are characterized by the deposition of misfolded protein fibrils in various organs. Deposited amyloid may be removed by a phagocyte-dependent innate...
7.
Mori M, Dai J, Miyahara H, Li Y, Kang X, Yoshimi K, et al.
Exp Anim
. 2022 Nov;
72(2):233-241.
PMID: 36450519
The Matsumoto Eosinophilia Shinshu (MES) is a rat model for hereditary blood eosinophilia. The incidence of eosinophilia is 100% in both female and male MES. The primary cause of the...
8.
Cui X, Sawashita J, Dai J, Liu C, Igarashi Y, Mori M, et al.
Dis Model Mech
. 2022 Jan;
15(3).
PMID: 35099007
Exercise interventions are beneficial for reducing the risk of age-related diseases, including amyloidosis, but the underlying molecular links remain unclear. Here, we investigated the protective role of interval exercise training...
9.
Mori M, Liu C, Yoshizawa T, Miyahara H, Dai J, Igarashi Y, et al.
Mamm Genome
. 2022 Jan;
33(3):451-464.
PMID: 35067752
The Nakano cataract mouse (NCT) manifests a wavy coat for their first hair as a genetic trait. In this study, we explored the molecular genetic basis of the wavy coat....
10.
Liu C, Miyahara H, Dai J, Cui X, Li Y, Kang X, et al.
Exp Eye Res
. 2021 Dec;
215:108905.
PMID: 34968474
The BALB.NCT-Cpox is a mutant mouse model for hereditary cataracts. We previously uncovered that the primary cause of the cataracts of BALB.NCT-Cpox is a mutation in the coproporphyrinogen oxidase (Cpox)...