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KayLee K Steiner

Explore the profile of KayLee K Steiner including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 76
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Recent Articles
1.
Arner E, Jennings E, Crooks D, Ricketts C, Wolf M, Cottam M, et al.
bioRxiv . 2025 Jan; PMID: 39829901
Metastasis causes most cancer deaths and reflects transitions from primary tumor escape to seeding and growth at metastatic sites. Epithelial-to-mesenchymal transition (EMT) is important early in metastasis to enable cancer...
2.
Heintzman D, Sinard R, Fisher E, Ye X, Patterson A, Elasy J, et al.
Sci Immunol . 2024 Sep; 9(99):eadp3475. PMID: 39303018
Heat is a cardinal feature of inflammation, yet its impacts on immune cells remain uncertain. We show that moderate-grade fever temperatures (39°C) increased murine CD4 T cell metabolism, proliferation, and...
3.
Patterson A, Needle G, Sugiura A, Jennings E, Chi C, Steiner K, et al.
Sci Immunol . 2024 Aug; 9(98):eadh0368. PMID: 39151020
Inborn errors of metabolism (IEMs) and immunity (IEIs) are Mendelian diseases in which complex phenotypes and patient rarity have limited clinical understanding. Whereas few genes have been annotated as contributing...
4.
Steiner K, Young A, Patterson A, Jennings E, Chi C, Hatem Z, et al.
bioRxiv . 2024 Jul; PMID: 39026793
Lipid metabolism is fundamental to CD4+ T cell metabolism yet remains poorly understood across subsets. Therefore, we performed targeted in vivo CRISPR/Cas9 screens to identify lipid-associated genes essential for T...
5.
Bader J, Wolf M, Lupica-Tondo G, Madden M, Reinfeld B, Arner E, et al.
Nature . 2024 Jul; 631(8022):E16. PMID: 38982216
No abstract available.
6.
Bader J, Wolf M, Lupica-Tondo G, Madden M, Reinfeld B, Arner E, et al.
Nature . 2024 Jun; 630(8018):968-975. PMID: 38867043
Obesity is a leading risk factor for progression and metastasis of many cancers, yet can in some cases enhance survival and responses to immune checkpoint blockade therapies, including anti-PD-1, which...
7.
Wolf M, Madden M, Arner E, Bader J, Ye X, Vlach L, et al.
J Clin Invest . 2024 Apr; 134(8. PMID: 38618956
Clear cell renal cell carcinoma (ccRCC) is characterized by dysregulated hypoxia signaling and a tumor microenvironment (TME) highly enriched in myeloid and lymphoid cells. Loss of the von Hippel Lindau...
8.
Patterson A, Needle G, Sugiura A, Chi C, Steiner K, Fisher E, et al.
bioRxiv . 2023 Feb; PMID: 36747715
Highlights: Inborn errors of immunity and metabolism have greater overlap than previously known deficiency causes an IEM but also selectively regulates T cell subset fate Loss of causes a T...
9.
El-Kenawi A, Dominguez-Viqueira W, Liu M, Awasthi S, Abraham-Miranda J, Keske A, et al.
Cancer Res . 2021 Jul; 81(21):5477-5490. PMID: 34301759
Castration-resistant prostate cancer (CRPC) is a lethal stage of disease in which androgen receptor (AR) signaling is persistent despite androgen deprivation therapy (ADT). Most studies have focused on investigating cell-autonomous...
10.
Cavanaugh N, Parthasarathy A, Wong N, Steiner K, Chu J, Adjei J, et al.
BMC Res Notes . 2021 Jun; 14(1):230. PMID: 34103082
Objective: In order to isolate and identify bacteria that produce potentially novel bactericidal/bacteriostatic compounds, two ponds on the campus of the Rochester Institute of Technology (RIT) were targeted as part...