Kavitha Govindasamy
Overview
Explore the profile of Kavitha Govindasamy including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
107
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Recent Articles
1.
Yu C, He S, Zhu W, Ru P, Ge X, Govindasamy K
Front Cell Infect Microbiol
. 2023 Jul;
13:1202138.
PMID: 37424781
Cancer is one of the leading causes of death worldwide. Human cytomegalovirus (HCMV), a well-studied herpesvirus, has been implicated in malignancies derived from breast, colorectal muscle, brain, and other cancers....
2.
Jaijyan D, Govindasamy K, Lee M, Zhu H
Cell Rep Methods
. 2022 Sep;
2(9):100287.
PMID: 36160049
The development of a chemically attenuated, replication-incompetent virus vaccine can provide protection against diseases caused by DNA viruses. In this study, we have developed a method to produce live-attenuated, replication-defective...
3.
Jaijyan D, Govindasamy K, Singh J, Bhattacharya S, Prasad Singh A
Sci Rep
. 2020 Sep;
10(1):15614.
PMID: 32973208
Babesia microti, an emerging human pathogen, is primarily transmitted through a bite of an infected tick and blood transfusions in human. Stable transfection technique has been reported in many protozoan...
4.
Govindasamy K, Bhanot P
PLoS Pathog
. 2020 Sep;
16(8):e1008131.
PMID: 32866196
Invasion of hepatocytes by Plasmodium sporozoites initiates the pre-erythrocytic step of a malaria infection. Subsequent development of the parasite within hepatocytes and exit from them is essential for starting the...
5.
Shi X, Hai L, Govindasamy K, Gao J, Coppens I, Hu J, et al.
Mol Microbiol
. 2020 May;
114(3):454-467.
PMID: 32432369
Reticulon and REEP family of proteins stabilize the high curvature of endoplasmic reticulum (ER) tubules. Plasmodium berghei Yop1 (PbYop1) is a REEP5 homolog in Plasmodium. Here, we characterize its function...
6.
Kirkman L, Zhan W, Visone J, Dziedziech A, Singh P, Fan H, et al.
Proc Natl Acad Sci U S A
. 2018 Jul;
115(29):E6863-E6870.
PMID: 29967165
We describe noncovalent, reversible asparagine ethylenediamine (AsnEDA) inhibitors of the proteasome (Pf20S) β5 subunit that spare all active subunits of human constitutive and immuno-proteasomes. The compounds are active against erythrocytic,...
7.
Panchal D, Govindasamy K, Rana A, Bhanot P
Mol Biochem Parasitol
. 2012 Mar;
184(1):52-4.
PMID: 22450301
Conditional mutagenesis is a powerful tool for genetic analysis in Plasmodium berghei. It allows the study of proteins that function both during the parasite's pre-erythocytic and erythrocytic development. Currently available...