Kavi Devraj
Overview
Explore the profile of Kavi Devraj including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
1467
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Recent Articles
1.
Devraj K, Kulkarni O, Liebner S
Metab Brain Dis
. 2024 Dec;
40(1):61.
PMID: 39671124
The blood-brain barrier (BBB) is formed by microvascular endothelial cells which are ensembled with pericytes, astrocytes, microglia and neurons in the neurovascular unit (NVU) that is crucial for neuronal function....
2.
Roesler J, Spitzer D, Jia X, Aasen S, Sommer K, Roller B, et al.
Neuro Oncol
. 2024 Jun;
26(11):2084-2099.
PMID: 38831719
Background: Brain metastases (BM) constitute an increasing challenge in oncology due to their impact on neurological function, limited treatment options, and poor prognosis. BM occurs through extravasation of circulating tumor...
3.
Peng H, Xin S, Pfeiffer S, Muller C, Merl-Pham J, Hauck S, et al.
Cell Death Dis
. 2024 Apr;
15(4):286.
PMID: 38653992
The progression of human degenerative and hypoxic/ischemic diseases is accompanied by widespread cell death. One death process linking iron-catalyzed reactive species with lipid peroxidation is ferroptosis, which shows hallmarks of...
4.
Laub V, Devraj K, Elias L, Schulte D
BMC Genomics
. 2023 Jul;
24(1):382.
PMID: 37420172
Background: Genomics data is available to the scientific community after publication of research projects and can be investigated for a multitude of research questions. However, in many cases deposited data...
5.
Spitzer D, Khel M, Putz T, Zinke J, Jia X, Sommer K, et al.
Nat Protoc
. 2023 Mar;
18(5):1510-1542.
PMID: 36859615
The neurovascular unit (NVU), composed of endothelial cells, pericytes, juxtaposed astrocytes and microglia together with neurons, is essential for proper central nervous system functioning. The NVU critically regulates blood-brain barrier...
6.
Schumacher L, Slimani R, Zizmare L, Ehlers J, Kleine Borgmann F, Fitzgerald J, et al.
Biomedicines
. 2023 Jan;
11(1).
PMID: 36672722
The blood-brain barrier (BBB) is a selectively permeable boundary that separates the circulating blood from the extracellular fluid of the brain and is an essential component for brain homeostasis. In...
7.
Reiss Y, Bauer S, David B, Devraj K, Fidan E, Hattingen E, et al.
Brain Pathol
. 2023 Jan;
33(2):e13147.
PMID: 36599709
The blood-brain barrier (BBB) is a physiological barrier maintaining a specialized brain micromilieu that is necessary for proper neuronal function. Endothelial tight junctions and specific transcellular/efflux transport systems provide a...
8.
Spitzer D, Puetz T, Armbrust M, Dunst M, Macas J, Croll F, et al.
Sci Rep
. 2022 Dec;
12(1):20925.
PMID: 36463381
Ischemic stroke is a serious neurological disorder that is associated with dysregulation of the neurovascular unit (NVU) and impairment of the blood-brain barrier (BBB). Paradoxically, reperfusion therapies can aggravate NVU...
9.
Spitzer D, Guerit S, Puetz T, Khel M, Armbrust M, Dunst M, et al.
Acta Neuropathol
. 2022 Jun;
144(2):305-337.
PMID: 35752654
Blood-brain barrier (BBB) dysfunction, characterized by degradation of BBB junctional proteins and increased permeability, is a crucial pathophysiological feature of acute ischemic stroke. Dysregulation of multiple neurovascular unit (NVU) cell...
10.
Fouani Y, Kirchhof L, Stanicek L, Luxan G, Heumuller A, Knau A, et al.
EMBO Rep
. 2022 May;
23(6):e54157.
PMID: 35527520
Vascular integrity is essential for organ homeostasis to prevent edema formation and infiltration of inflammatory cells. Long non-coding RNAs (lncRNAs) are important regulators of gene expression and often expressed in...